Main description:

This timely volume explores various techniques for tissue and organ regeneration using stem cells isolated from adult tissues. It discusses alternative explanations of stem cell plasticity as well as current clinical results with adult stem cell therapies. It examines the presence of potential pluripotent stem cells in adult tissues, paracrine effects of stem cell therapies, and involvement of exosomes and microparticles into observed phenomena. Fifteen chapters, all written by noted leaders of their fields, focus on a variety of topics including cord blood and hematopoietic stem cells, skin and tissue organ regeneration, very small embryonic-like stem cells, and cell therapies in cardiology, neonatology, and neurology. Edited by Dr. Mariusz Ratajczak, an internationally known specialist in adult stem cell biology, Adult Stem Cell Therapies: Alternatives to Plasticity is an important addition to the Stem Cell Biology and Regenerative Medicine series.

Contents:

.- 1 Regenerative Medicine and the Search for Pluripotent/Multipotent Stem Cells

.- Mariusz Z. Ratajczak

.- 2 Novel Therapeutic Approaches in Regenerative Medicine: Adult Tissue-Derived Very Small Embryonic like Stem Cells and Harnessing Paracrine Signals of Adult Stem Cells

.- Magda Kucia, Malwina Suszynska, Janina Ratajczak & Mariusz Z. Ratajczak

.- 3 Cord Blood Stem Cells

.- Marta Adamiak, Zbigniew Madeja and Ewa K. Zuba-Surma

.- 4 Human CD34-negative Hematopoietic Stem Cells

.- Yoshiaki Sonoda

.- 5 Cell Therapies in Cardiology

.- Wojciech Wojakowski, Agata Czekaj and Michal Tendera

.- 6 Mechanisms Regulating Trafficking of Stem Cells in Ischemic Heart Disease

.- Yuri Klyachkin, Ahmed Abdel-Latif

.- 7 Stem Cell Therapies in Neurology

.- Naoki Tajiri, Meaghan Staples, Sandra Acosta, Mibel Pabon, Travis Dailey, Yuji Kaneko, Cesar V. Borlongan

.- 8 Stem Cell Compartment in Acute Psychotic Syndromes

.- Jolanta Kucharska-Mazur, Jerzy Samochowiec

.- 9 Skin Regeneration and Circulating Stem Cells

.- Julia Borowczyk, Justyna Drukala

.- 10 Stem Cell Therapies in Neonatology

.- Boguslaw Machalinski

.- 11 Pluripotent Very Small Embryonic-like Stem Cells in Adult Mammalian Gonads

.- Deepa Bhartiya, Seema Parte, Hiren Patel, Sandhya Anand, Kalpana Sriraman, Pranesh Gunjal

.- 12 Molecular Signature of Very Small Embryonic Like Stem Cells

.- Hyunsook Kang, Jisun Lim, Jinbeom Heo, Jaeho Jeong, YongHwan Kim, Dong-Myung Shin

.- 13 Role of Extracellular Vesicles in Tissue/Organ Regeneration

.- Maria Chiara Deregibus, Alessandra Iavello, Ciro Tetta, Giovanni Camussi

.- 14 Extracellular Vesicles and Tissue Organ Regeneration

.- P. Quesenberry, J. Aliotta, M. Dooner, D. Chatterjee, B. Ramratnam, L. Goldberg, M. Del Tatto, M. Pereira, A. Sorokina, S. Wen

.- 15 Stem Cells in Infection and Sepsis

.- Tomasz Skirecki, Grazyna Hoser, Jerzy Kawiak.