Main description:

Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics, including taxane-anti-androgens cross-resistance in advanced prostate cancer and proteasome inhibitors in the treatment of multiple myeloma.

Contents:

1. Unravelling the Complexity and Functions of MTA Coregulators in Human Cancer
Da-Qiang Li, Rakesh Kumar
2. Examination of Epigenetic and other Molecular Factors Associated with mda-9/Syntenin Dysregulation in Cancer Through Integrated Analyses of Public Genomic Datasets
Manny D. Bacolod , Swadesh K. Das , Upneet K. Sokhi, Steven Bradley , David A. Fenstermacher , Maurizio Pellecchia, Luni Emdad, Devanand Sarkar and Paul B. Fisher
3. Exploitation of the Androgen Receptor to Overcome Taxane Resistance in Advanced Prostate Cancer
Sarah K. Martin and Natasha Kyprianou
4. Stem Cell-Based Therapies for Cancer
Deepak Bhere and Khalid Shah
5. Emerging Therapeutic Strategies for Overcoming Proteasome Inhibitor Resistance
Nathan G. Dolloff
6. Influence of Bone Marrow Microenvironment on Leukemic Stem Cells: Breaking up an Intimate Relationship
Puneet Agarwal and Ravi Bhatia
7. Perspectives on Epidermal Growth Factor Receptor Regulation in Triple-negative Breast Cancer: Ligand-mediated Mechanisms of Receptor Regulation and Potential for Clinical Targeting
Carly Bess Williams, Adam C. Soloff, Stephen P. Ethier, and Elizabeth S. Yeh
8. The Quest for an Effective Treatment for an Intractable Cancer: Established and Novel Therapies for Pancreatic Adenocarcinoma
Bridget A. Quinn, Nathaniel A. Lee, Timothy P. Kegelman, Praveen Bhoopathi, Luni Emdad, Swadesh K. Das, Maurizio Pellecchia, Devanand Sarkar and Paul B. Fisher