Main description:

Advances in Immunology, Volume 139, the latest issue of a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, with this release including chapters on Alzheimer's and its innate receptors, the field of immune orchestration by small molecules, like chemokines and lipids, the role of AID in the first checkpoint, and the design of vaccine strategies to elicit HIV-1 broadly neutralizing antibodies.

Contents:

1. The Microglial Response to Neurodegenerative Disease Wilbur M. Song and Marco Colonna 2. The First Tolerance Checkpoint in Mice and Humans: Control by AID Masayuki Kuraoka, Eric Meffre and Garnett Kelsoe 3. RAG Chromatin Scanning During V(D)J Recombination and Chromatin Loop Extrusion are Related Processes Sherry Lin, Zhaoqing Ba, Frederick W. Alt and Yu Zhang