Main description:

This volume of International Review of Neurobiology brings together cutting-edge research on advances in the neurochemistry and neuropharmacology of Tourette syndrome. It reviews current knowledge and understanding, provides a starting point for researchers and practitioners entering the field, and includes important topics regards tics, neurotransmitters, pharmacology and emerging treatments.

Contents:

An Introduction to the Clinical Phenomenology of Tourette Syndrome
Davide Martino, Namrata Madhusudan, Panagiotis Zis and Andrea E. Cavanna

Functional Neuroanatomy of Tics
Irene Neuner, Frank Schneider and N. Jon Shah

Functional Imaging of Dopaminergic Neurotransmission in Tourette Syndrome
Barbara Segura and Antonio P. Strafella

Non-dopaminergic neurotransmission in the pathophysiology of Tourette syndrome
Patrick T. Udvardi, Ester Nespoli, Francesca Rizzo, Bastian Hengerer and Andrea G. Ludolph

Reinforcement Learning and Tourette Syndrome
Stefano Palminteri and Mathias Pessiglione

Genetic Susceptibility and Neurotransmitters in Tourette Syndrome
Peristera Paschou, Thomas V. Fernandez, Frank Sharp, Gary A. Heiman and Pieter J. Hoekstra

Pharmacological Animal Models of Tic Disorders
Kevin W McCairn and Masaki Isoda

Animal Models Recapitulating the Multifactorial Origin of Tourette Syndrome
Simone Macri, Martina Proietti Onori, Veit Roessner and Giovanni Laviola

Neuroendocrine Aspects of Tourette Syndrome
Davide Martino, Antonella Macerollo and James F Leckman

Clinical Pharmacology of Dopamine-Modulating Agents in Tourette`s Syndrome
Sabine Mogwitz, Judith Buse, Stefan Ehrlich and Veit Roessner

Clinical Pharmacology of Non-Dopaminergic Drugs in Tourette Syndrome
Andreas Hartmann

Antiepileptic Drugs and Tourette Syndrome
Andrea E. Cavanna and Andrea Nani

Clinical Pharmacology of Co-Morbid Obsessive-Compulsive Disorder in Tourette Syndrome
Valeria Neri and Francesco Cardona

Clinical Pharmacology of Comorbid Attention Deficit Hyperactivity Disorder in Tourette Syndrome
Renata Rizzo and Mariangela Gulisano

Emerging Treatment Strategies in Tourette syndrome: What's in the Pipeline?
C. Termine, C. Selvini, G. Rossi and U. Balottin

Tics and Other Stereotyped Movements as Side Effects of Pharmacological Treatment Marcos Madruga-Garrido and Pablo Mir