Main description:

From molecular biology to clinical applications of selective receptor blockade, the present volume compiles the latest advances of this emerging field. Of particular importance is the attention given to the newly discovered AT2 receptors, and the physiology and pathophysiology of angiotensin receptor subtypes. The book will provide clinicians treating cardiovascular disease and hypertension with a clearer understanding of this therapeutically important and complicated hormone.

Contents:

Angiotensin II Receptor (T. Inagami et al.). Molecular Biology of Angiotensin II Receptors (B. Lassegue et al.). Defining Angiotensin Receptor Subtypes (A.T. Chiu et al.). Medicinal Chemistry of Angiotensin II Antagonists (W.J. Greenlee, R.W. Wexler). The Angiotensin II AT2 Receptor Subtype (M. de Gasparo et al.). Medicinal Chemistry of AT2 Receptors (J.J. Edmonds, J.C. Hodges). Pharmacology of AT2 Receptors (J.A. Keiser, R.L. Panek). Brain Angiotensin II Receptor Subtypes (J.M. Saavedra). Second Messengers for Brain Angiotensin Receptor Subtypes (F.M.J. Heemskerk, J.M. Saavedra). Angiotensin Receptor Subtypes and Cerebral Blood Flow (C. Stroemberg et al.). Angiotensin II Receptor Subtypes and Growth (M. Viswanathan, J.M. Saavedra). Inhibiting Effects of Angiotensin II on Cardiovascular Hypertrophy in Experimental Hypertension (J.J. Morton). Inhibiting the Effects of Angiotensin on Cardiovascular Hypertrophy (K.P. Metsarinne et al.). 8 additional articles. Index.