Main description:

Animal experiments have contributed much to our understanding of mechanisms of disease and are important for determining new therapies. Animal Models of Human Disease reviews the latest research and developments in this field.

Contents:

1. Modelling cancers in Drosophila

Dr. Lucas Waltzer

2. Modeling human prostate cancer in mice

Dr. Fen Wang

3. The Drosophila heart: a model system for the genetics of cardiac disease and senescence

Dr. Robert Wessells

4. Dissection of cardiovascular development and disease pathways in zebrafish

John D. Mably

5. Transgenic mouse models of human cardiovascular and blood diseases

Dr. Simon J. Conway

6. 800 Facets of Retinal Degeneration

Dr. Andrew C. Zelhof

7. Towards a better understanding of human eye disease: insights from the zebrafish, Danio rerio

Dr. Jeffrey M Gross

8. Mouse models of retinal disease

Dr. Paul N. Baird

9. Eating on the Fly: Studying Metabolic Diseases in Drosophila melanogaster

Dr David Tree

10. Mouse models of selected inborn errors of metabolism

William J. Craigen

11. Modeling disoders of mitochondrial fatty acid metabolism in the mouse

Dr. Eric Goetzman

12. Watching Worms Whither: Modeling Neurodegeneration in C. elegans

Dr. Benjamin Wolozin

13. Demise of the Flies?: Why Drosophila Models Still Matter

George R. Jackson

14. Utility of zebrafish to late-onset neurology: A developmental model coming of age

W. Ted Allison

15. Genetic Mouse Models of Neurodegenerative Diseases

Darren J. Moore