Main description:

This book summarizes the emerging trends in the field of antibiotic resistance of various gram-negative and gram-positive bacterial species. The ability of different species of bacteria to resist the antimicrobial agent has become a global problem. As such, the book provides a comprehensive overview of the advances in our understanding of the origin and mechanism of resistance, discusses the modern concept of the biochemical and genetic basis of antibacterial resistance and highlights the clinical and economic implications of the increased prevalence of antimicrobial resistant pathogens and their ecotoxic effects. It also reviews various strategies to curtail the emergence and examines a number of innovative therapeutic approaches, such as CRISPR, phage therapy, nanoparticles and natural antimicrobials, to combat the spread of resistance.

Contents:

Chapter 1. Emergence of antibiotic resistant bacteria.- Chapter 1.1. Era of antibiotic discovery.- Chapter 1.2. Emergence of antibiotic resistant microbes immediate after the discovery of antibiotics.- Chapter 1.3. Newly discovered antibiotics of 21st century.- Chapter 2. Impact of antibiotic resistant bacteria on different field.- Chapter 2.1. Antibiotic resistance: Role and pattern in different class of bacteria.- Chapter 2.2. Effect of drug resistant bacteria on agriculture, medical society, livestock and environment.- Chapter 3. Antibiotic resistance: Pattern and Mechanisms.- Chapter 3.1. Intrinsic antibiotic resistant mechanism in bacteria.- Chapter 3.2. Extrinsic antibiotic resistant mechanism in bacteria .- Chapter 3.3. Chemical mediated alteration of antibiotics.- Chapter 4.1. Novel strategies for overcoming of antibiotic resistant mechanisms.- Chapter 4.2. Collapsing of antibiotic resistance with the help of genetic approaches.- Chapter 4.3. Bacteriophage: A new hope for the control of antibiotic resistant bacteria.- Chapter 4.4. Nanotechnology: A 21st Century approach towards the control of antibiotic resistant bacteria.- Chapter 5. Future Prospects.