Main description:

This book provides a comprehensive, state-of-the-art account of the role of immunohistochemistry in the diagnosis of skin tumors, which is crucial given that overlapping histologic features and unusual morphologic changes can lead to considerable diagnostic uncertainty. The book reviews in detail the sensitivity and specificity of commonly available antibodies and their pattern of immunostaining. readers will learn when to order antibodies and how to interpret findings. In addition, prognostic markers are evaluated and emphasis placed on the pitfalls commonly encountered when evaluating these neoplasms. The text is complemented by a wealth of superb images. Helpful histograms and algorithms are included, and clear guidance is provided on the application and interpretation of less commonly used antibodies and immunostains. Applied Immunohistochemistry in the Evaluation of Skin Neoplasms will serve as an extremely valuable resource for practicing dermatopathologists and pathologists.

Contents:

Contents

List
of Contributors

Part
I: Immunohistology of Epithelial Tumors

1 Immunohistology and Molecular Studies
of Epithelial Tumors

Heather M. Froehlich and Jose A.
Plaza

Part II: Adnexal
Neoplasms

2 Immunohistology and Molecular Studies
of Sweat Gland Tumors

Ana M. Molina-Ruiz, Laura Fuertes,
and Luis Requena

3 Immunohistology and Molecular Studies
of Follicular Tumors

Olayemi Sokumbi and Jose A. Plaza

4 Use of Immunohistochemical and
Molecular Studies in the Evaluation of the Sebaceous Neoplasms

Doina Ivan, Victor G. Prieto, and
Phyu P. Aung

Part III:
Immunohistology of Cutaneous Metastases and Its Simulators

5 Cutaneous Metastasis

Danielle M. Wehle, Sadia Salim, and
Martin A. Sangueza

Part IV:
Immunohistology of Mesenchymal Neoplasms

6 Immunohistology and Molecular Studies
of Fibrohistiocytic and Myofibroblastic Cutaneous Tumors

Danny Ghazarian, Sebastien Labonte,
Brendan Craig Dickson, and Ayman Al Habeeb

7 Immunohistology and Molecular Studies
of Smooth Muscle and Neural Cutaneous Tumors

Tammie Ferringer

8 New Insights in Vascular Lesions
Development and Identification with Immunohistochemical Markers

Omar P.
Sangueza
and Julio A. Diaz-Perez

Part V:
Immunohistology of Cutaneous Lymphoma

9 Immunohistology and Molecular Studies
of Cutaneous B-cell Lymphomas

Juan F. Garcia

10 Immunohistology and Molecular Studies of
Cutaneous T-cell Lymphomas and Mimics

Carlos A. Torres-Cabala, Phyu P.
Aung, Roberto N. Miranda, and Jonathan L. Curry

11 Immunohistology of Leukemia Cutis and
Histiocytic Tumors

Maria Teresa Fernandez Figueras,
Gustavo Tapia, Jose Luis Mate, Aurelio Ariza

Part VI:
Immunohistology of Melanocytic Lesions

12 Immunohistology of Melanocytic Lesions

Jonathan L. Curry, Michael T.
Tetzlaff, Priyadharsini Nagarajan, and Carlos A. Torres-Cabala

Part VII:
Molecular Studies of Melanocytic Lesions

13 Molecular Studies of Melanocytic Lesions

Rami Al-Rohil, Priyadharsini
Nagarajan, and Michael T. Tetzlaff

Part VIII:
Immunohistology of Sentinel Lymph Node in Melanoma

14 Sentinel Lymph Node in Melanoma

Victor G. Prieto