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Master key pharmacological concepts and practices with the most comprehensive, authoritative guide available

Presented in full-color and packed with hundreds of illustrations, Basic and Clinical Pharmacology is the wide-ranging, engaging guide students have counted on for decades.

Organized to reflect the course sequence in many pharmacology courses and in integrated curricula, the guide covers the important concepts students need to know about the science of pharmacology and its application to clinical practice. This edition has been extensively updated to provide expanded coverage of transporters, pharmacogenomics, and new drugs

Delivers the knowledge and insight needed to excel in every facet of pharmacology!.

Encompasses all aspects of medical pharmacology, including botanicals and over-the-counter drugs
Major revisions of the chapters on immunopharmacology, antiseizure, antipsychotic, antidepressant, antidiabetic, anti-inflammatory, and antiviral drugs, prostaglandins, and central nervous system neurotransmitters
New chapter on the increasingly relevant topic of cannabis pharmacology
Each chapter opens with a case study, covers drug groups and prototypes, and closes with summary tables and diagrams that encapsulate important information
Revised full-color illustrations provide more information about drug mechanisms and effects and help clarify important concepts
Trade Name/Generic Name tables are provided at end of each chapter for easy reference when writing a chart order or prescription
Includes descriptions of important new drugs released through May 2019
New and updated coverage of general concepts relating to recently discovered receptors, receptor mechanisms, and drug transporters

Contents:

Preface
Preface for Indian Version
Authors
Section I Basic Principles

1. Introduction: The Nature of Drugs & Drug Development & Regulation
2. Drug Receptors & Pharmacodynamics
3. Pharmacokinetics & Pharmacodynamics: Rational Dosing & the time Course of Drug Action
4. Drug Biotransformation
5. Pharmacogenomics

Section II Autonomic Drugs

6. Introduction to Autonomic Pharmacology
7. Cholinoceptor-Activating & Cholinesterase-Inhibiting Drugs
8. Cholinoceptor-Blocking Drugs
9. Adrenoceptor Agonists & Sympathomimetic Drugs
10. Adrenoceptor Antagonist Drugs

Section III Cardiovascular-Renal Drugs

11. Antihypertensive Agents
12. Vasodilators & the Treatment of Angina Pectoris
13. Drugs Used in Heart Failure
14. Agents Used in Cardiac Arrhythmias
15. Diuretic Agents

Section IV Drugs with Important Actions on Smooth Muscle

16. Histamine, Serotonin, & the Ergot Alkaloids
17. Vasoactive Peptides
18. The Eicosanoids: Prostaglandins, Thromboxanes, Leukotrienes, & Related Compounds
19. Nitric Oxide
20. Drugs Used in Asthma & Chronic Obstructive Pulmonary Disease

Section V Drugs That Act in the Central Nervous System

21. Introduction to the Pharmacology of CNS Drugs
22. Sedative-Hypnotic Drugs
23. The Alcohols
24. Antiseizure Drugs
25. General Anesthetics
26. Local Anesthetics
27. Skeletal Muscle Relaxants
28. Pharmacologic Management of Parkinsonism & Other Movement Disorders
29. Antipsychotic Agents & Lithium
30. Antidepressant Agents
31. Opioid Agonists & Antagonists
32. Drugs of Abuse

Section VI Drugs Used to Treat Diseases of the Blood, Inflammation, & Gout

33. Agents Used in Cytopenias; Hematopoietic Growth Factors
34. Drugs Used in Disorders of Coagulation
35. Agents Used in Dyslipidemia
36. Nonsteroidal Anti-Inflammatory Drugs, Disease-Modifying Antirheumatic Drugs, Nonopioid Analgesics, & Drugs Used in Gout

Section VII Endocrine Drugs

37. Hypothalamic & Pituitary Hormones
38. Thyroid & Antithyroid Drugs
39. Adrenocorticosteroids & Adrenocortical Antagonists
40. The Gonadal Hormones & Inhibitors
41. Pancreatic Hormones & Glucose-Lowering Drugs
42. Agents That Affect Bone Mineral Homeostasis

Section VIII Chemotherapeutic Drugs

43. Beta-Lactam & Other Cell Wall- & Membrane-Active Antibiotics
44. Tetracyclines, Macrolides, Clindamycin, Chloramphenicol, Streptogramins, Oxazolidinones, & Pleuromutilins
45. Aminoglycosides & Spectinomycin
46. Sulfonamides, Trimethoprim, & Quinolones
47. Antimycobacterial Drugs
48. Antifungal Agents
49. Antiviral Agents
50. Miscellaneous Antimicrobial Agents; Disinfectants, Antiseptics, & Sterilants
51. Clinical Use of Antimicrobial Agents
52. Antiprotozoal Drugs
53. Pharmacology of the Antihelminthic Drugs
54. Cancer Chemotherapy
55. Immunopharmacology

Section IX Toxicology

56. Introduction to Toxicology: Occupational & Environmental
57. Heavy Metal Intoxication & Chelators
58. Management of the Poisoned Patient

Section X Special Topics

59. Special Aspects of Perinatal & Pediatric Pharmacology
60. Special Aspects of Geriatric Pharmacology
61. Dermatologic Pharmacology
62. Drugs Used in the Treatment of Gastrointestinal Diseases
63. Cannabinoid Drugs
64. Therapeutic & Toxic Potential of Over-the-Counter Agents
65. Dietary Supplements & Herbal Medications
66. Rational Prescribing & Prescription Writing
67. Important Drug Interactions & Their Mechanisms

Appendix: Vaccines, Immune Globulins, & Other Complex Biologic Products
Index