Main description:

The book appears in two volumes, the first dealing primarily with chemical and structural aspects, and the second with metabolic aspects. The purpose is not only to review recent work on chemical and physiological aspects of bilirubin scructure and metabolism, but also to emphasize the importance of methodological advances and their potential in future studies.

Contents:

1. Heme Degradation and Bilirubin Formation 2. Aspects of Bilirubin Transport 3. The Role of Conjugating Enzymes in the Biliary Excretion of Bilirubin 4. Formation, Metabolism and Properties of Pyrrolic Compounds Appearing in the Gut 5. The Role of Kinetic Analysis and Mathematical Modeling in the Study of Bilirubin Metabolism In Vivo 6. Physiology and Disorders of Human Bilirubin Metabolism