Main description:

Bio-inspired concepts for biomedical engineering are at the forefront of tissue engineering and regenerative medicine. Providing a comprehensive overview of the latest advances and techniques in the field, Bio-inspired Materials for Biomedical Engineering demonstrates the dramatic clinical breakthroughs that have been made in engineering all four of the major tissue types and modulating the immune system. Written by prominent leaders in the fields of materials engineering, chemical engineering, cell biology, and regenerative medicine, this groundbreaking text provides scientists, professors, postdocs, and graduate students with the dramatic clinical breakthroughs related to tissue engineering applications.

Contents:

Contributors vii Preface xi INTRODUCTION 1 Sang Jin Lee and Anthony Atala PART I ENGINEERING BIO-INSPIRED MATERIAL MICROENVIRONMENTS 5 CHAPTER 1 ECM-INSPIRED CHEMICAL CUES: BIOMIMETIC MOLECULES AND TECHNIQUES OF IMMOBILIZATION 7 Roger Y. Tam, Shawn C. Owen, and Molly S. Shoichet CHAPTER 2 DYNAMIC MATERIALS MIMIC DEVELOPMENTAL AND DISEASE CHANGES IN TISSUES 25 Matthew G. Ondeck and Adam J. Engler CHAPTER 3 THE ROLE OF MECHANICAL CUES IN REGULATING CELLULAR ACTIVITIES AND GUIDING TISSUE DEVELOPMENT 45 Liming Bian CHAPTER 4 CONTRIBUTION OF PHYSICAL FORCES ON THE DESIGN OF BIOMIMETIC TISSUE SUBSTITUTES 59 Menekse Ermis, Erkan Turker Baran, Tudba Dursun, Ezgi Antmen, and Vasif Hasirci CHAPTER 5 CELLULAR RESPONSES TO BIO-INSPIRED ENGINEERED TOPOGRAPHY 77 Chelsea M. Kirschner, James F. Schumacher, and Anthony B. Brennan CHAPTER 6 ENGINEERING THE MECHANICAL AND GROWTH FACTOR SIGNALING ROLES OF FIBRONECTIN FIBRILS 99 Christopher A. Lemmon CHAPTER 7 BIOLOGIC SCAFFOLDS COMPOSED OF EXTRACELLULAR MATRIX AS A NATURAL MATERIAL FOR WOUND HEALING 111 Elizabeth W. Kollar, Christopher L. Dearth, and Stephen F. Badylak CHAPTER 8 BIO-INSPIRED INTEGRATION OF NATURAL MATERIALS 125 Albino Martins, Marta Alves da Silva, Ana Costa-Pinto, Rui L. Reis, and Nuno M. Neves PART II BIO-INSPIRED TISSUE ENGINEERING 151 CHAPTER 9 BIO-INSPIRED DESIGN OF SKIN REPLACEMENT THERAPIES 153 Dennis P. Orgill CHAPTER 10 EPITHELIAL ENGINEERING: FROM SHEETS TO BRANCHED TUBES 161 Hye Young Kim and Celeste M. Nelson CHAPTER 11 A BIOMIMETIC APPROACH TOWARD THE FABRICATION OF EPITHELIAL-LIKE TISSUE 175 Hongjun Wang and Meng Xu CHAPTER 12 NANO- AND MICROSTRUCTURED ECM AND BIOMIMETIC SCAFFOLDS FOR CARDIAC TISSUE ENGINEERING 195 Quentin Jallerat, John M. Szymanski, and Adam W. Feinberg CHAPTER 13 STRATEGIES AND CHALLENGES FOR BIO-INSPIRED CARDIOVASCULAR BIOMATERIALS 227 Elaine L. Lee and Joyce Y. Wong CHAPTER 14 EVALUATION OF BIO-INSPIRED MATERIALS FOR MINERALIZED TISSUE REGENERATION USING TYPE I COLLAGEN REPORTER CELLS 259 Liisa T. Kuhn, Emily Jacobs, and A. Jon Goldberg CHAPTER 15 LEARNING FROM TISSUE EQUIVALENTS: BIOMECHANICS AND MECHANOBIOLOGY 281 David D. Simon and Jay D. Humphrey CHAPTER 16 MIMICKING THE HEMATOPOIETIC STEM CELL NICHE BY BIOMATERIALS 309 Eike Muller, Michael Ansorge, Carsten Werner, and Tilo Pompe CHAPTER 17 ENGINEERING IMMUNE RESPONSES TO ALLOGRAFTS 327 Anthony W. Frei and Cherie L. Stabler CHAPTER 18 IMMUNOMIMETIC MATERIALS 357 Jamal S. Lewis and Benjamin G. Keselowsky Index 371