Main description:

This book focuses on biodegradable polymers that are already in clinical use or under clinical development. Synthetic and natural polymers will be included. This excludes polymers that have been investigated and did not reach clinical development. The purpose of this book is to provide updated status of the polymers that are clinical use and those that are now being developed for clinical use and hopefully will reach the clinic during the next 5 years. The book provides information that of interest to academics and practicing researchers including chemists, biologists and bioengineers and users: physicians, pharmacists.

Contents:

CONTRIBUTORS. PREFACE. PART I GENERAL. 1 Biodegradable Polymers in Drug Delivery (Jay Prakash Jain, Wubante Yenet, Abraham J. Domb, and Neeraj Kumar). PART II BIODEGRADABLE POLYMERS OF NATURAL ORIGIN: PROTEIN-BASED POLYMERS. 2 Collagen (Wahid Khan, Deepak Yadav, Abraham J. Domb, and Neeraj Kumar). 3 Properties and Hemostatic Application of Gelatin (Jalindar Totre, Diana Ickowicz, and Abraham J. Domb). PART III BIODEGRADABLE POLYMERS OF NATURAL ORIGIN: POLYSACCHARIDES. 4 Chitosan and Its Derivatives in Clinical Use and Applications (Anuradha Subramanian, Kirthanashri Srinivasan Vasanthan, Uma Maheswari Krishnan, and Swaminathan Sethuraman). 5 Clinical Uses of Alginate (Udi Nussinovitch and Amos Nussinovitch). 6 Dextran and Pentosan Sulfate Clinical Applications (Ramu Parthasarathi and Athipettah Jayakrishnan). 7 Arabinogalactan in Clinical Use (Rajendra P. Pawar, Babasaheb A. Kushekar, Bhaskar S. Jadhav, Kiran R. Kharat, Ravikumar M. Borade, and Abraham J. Domb). PART IV BIODEGRADABLE POLYMERS OF NATURAL ORIGIN: POLYESTERS. 8 Polyhydroxyalkanoate (Kesaven Bhubalan, Wing-Hin Lee, and Kumar Sudesh). PART V SYNTHETIC BIODEGRADABLE POLYMERS. 9 Lactide and Glycolide Polymers (Kevin Letchford, Anders Sodergard, David Plackett, Samuel Gilchrist, and Helen Burt). 10 Polyanhydrides Poly(CPP-SA), Fatty-Acid-Based Polyanhydrides (Ravikumar M. Borade, Abraham J. Domb, Archana A. Sawale, Rajendra P. Pawar, and Kiran R. Kharat). 11 Poly(e-Caprolactone-co-Glycolide): Biomedical Applications of a Unique Elastomer (Kevin Cooper, Aruna Nathan, and Murty Vyakarnam). 12 Medicinal Applications of Cyanoacrylate (Rajendra P. Pawar, Ashok E. Jadhav, Sumangala B. Tathe, Bhimrao C. Khade, and Abraham J. Domb). 13 Polyethylene Glycol in Clinical Application and PEGylated Drugs (Teerapol Srichana, and Tan Suwandecha). PART VI INORGANIC POLYMERS. 14 Calcium-Phosphate-Based Ceramics for Biomedical Applications (Qing Lv, Kevin W.-H. Lo, Lakshmi S. Nair, and Cato T. Laurencin). PART VII BIODEGRADABLE POLYMERS FOR EMERGING CLINICAL USES. 15 Biocompatible Polymers for Nucleic Acid Delivery (Jeff Sparks, and Khursheed Anwer). 16 Biodegradable Polymers for Emerging Clinical Use in Tissue Engineering (Shalini Verma, Kalpna Garkhal, Anupama Mittal, and Neeraj Kumar). 17 Injectable Polymers (Shimon A. Unterman, Norman A. Marcus, and Jennifer H. Elisseeff). PART VIII IPR ASPECTS OF BIODEGRADABLE POLYMERS. 18 Global Patent and Technological Status of Biodegradable Polymers in Drug Delivery and Tissue Engineering (Parikshit Bansal, Shalini Verma, Wahid Khan, and Neeraj Kumar). Index.