Main description:

Abraham Rosenberg assembles the groundbreaking work of preeminent international scientists to provide the most current, state-of-the-art presentation of research in siabiology. This concise volume examines the historical development of the field and reviews current knowledge on the genetic, immunologic, oncologic, neurodevelopmental, pathogenic, and cell regulatory properties of sialic acid. Outstanding features of this work include exhaustive reference material and detailed information tables.

Contents:

The Beginnings of Sialic Acid (A. Rosenberg). Biochemistry and Role of Sialic Acids (R. Schauer et al.). Biological Specificity of Sialyltransferases (S. Basu et al.). Sialobiology and the Polysialic Acid Glycotope: Occurrence, Structure, Function, Synthesis and Glycopathology (F.A. Troy II). Biochemistry and Oncology of Sialoglycoproteins (V.P. Bhavanandan, K. Furukawa). Cellular Biology of Gangliosides (Y. Nagai, M. Iwamori). Role of Gangliosides in Transmembrane Signaling and Cell Recognition (S.I. Hakomori). Biochemistry and Function of Sialidases (M. Saito, R.K. Yu). Sialic Acid as Receptor Determinant of Ortho and Paramyxoviruses (G. Herrler et al.). Sialic Acid in Biochemical Pathology (K. Suzuki). Neurite Loss Caused by Ganglioside Undersialylation (A. Rosenberg). Index.