Contents:

1: The Bacterial Membrane.- I. Introduction.- II. Membranes and Surface Organization of the Bacterial Cell.- A. Surface Structures of Gram-Negative Bacteria.- B. Surface Structures of Gram-Positive Bacteria.- III. Intracellular Membrane Systems in Bacteria.- A. Mesosome Vesicles and Membranes.- B. Photosynthetic Membranes.- C. Membrane Vesicles, "Stacked" Membranes, Dissociation, and Gas Vacuoles.- D. Reticulum.- IV. Anatomy of Bacterial Membranes.- V. Chemical Composition of Isolated Membranes.- A. Gross Chemical Composition.- B. Lipids and Lipid-Soluble Components.- C. Proteins.- VI. Molecular Interactions in Membranes, Dissociation, and Reassociation.- A. Molecular Interactions.- B. Dissociation and Reassociation.- VII. Membrane Functions.- VIII. Biogenesis of Bacterial Membranes.- IX. Conclusions.- References.- 2: Complex Carbohydrates of Animal Cells: Biochemistry and Physiology of the Cell Periphery.- I. Complex Carbohydrate Structures.- A. Glycoproteins.- B. Glycosaminoglycans.- C. Glycolipids.- II. Biosynthesis of Complex Carbohydrate Structures.- A. General Features.- B. The Ultramicro Anatomy of Complex Carbohydrate Biosynthesis.- C. The Specificity of Glycosyl Transferases.- III. Complex Carbohydrates of Cells and Membranes.- A. General Features.- B. Studies of Isolated Plasma Membranes.- C. Nondisruptive Studies of Cell-Surface Carbohydrates.- D. Turnover and Regeneration of Cell-Surface Complex Carbohydrates.- IV. Function.- A. Cell Division and Surface Complex Carbohydrates.- B. Transport and Surface Complex Carbohydrates.- C. Antigens and Receptors of the Cell Surface.- D. Cellular Interactions.- E. Malignant Transformation 149 References.- 3: The Structure and Function of Sarcoplasmic Reticulum Membranes..- I. The Morphology of Sarcoplasmic Reticulum and Its Physiological Function.- II. Regulation of Sarcoplasmic Ca2+ Concentration by Sarcoplasmic Reticulum Membranes.- III. The Mechanism of Ca2+ Transport by Fragmented Sarcoplasmic Reticulum.- A. Preparation and Characterization of FSR.- B. Morphology of FSR.- C. The Energetics of Ca2+ Transport.- D. The Binding of ATP and ADP to Skeletal Muscle Microsomes.- E. ATP-ADP Exchange Reaction.- F. The Phosphoprotein Intermediate.- G. Specificity of the Transport System.- H. The Rate of Ca2+ Uptake.- I. The Effect of Ca2+-Precipitating Agents.- J. The State of Ca2+ Within the Microsomes.- IV. The Role of Phospholipids in the ATPase Activity and Ca2+ Transport of Sarcoplasmic Reticulum Membranes.- A. The Use of Phospholipases in the Analysis of the Role of Phospholipids in Sarcotubular Membranes.- B. Mode of Participation of Lecithin in ATPase Activity and Ca2+ Transport.- C. Extraction of Microsomes by Organic Solvents.- D. Effect of Phospholipases on Surface Membranes.- V. Effect of Proteolytic Enzymes on Ca2+ Transport.- VI. The Role of SH Groups.- VII. The Role of Sterols and the Effect of Detergents.- VIII. Attempts to Detect Conformational Change in Microsomal Membranes.- IX. The Release of Ca2+ from Sarcoplasmic Reticulum.- X. The Protein Composition of Sarcoplasmic Reticulum Membranes.- XI. Solubilization and Reconstitution of Microsomal Membranes.- XII. Inhibitors of Ca2+ Transport.- A. Caffeine.- B. Effects of Quinine and Quinidine on Sarcoplasmic Reticulum.- C. Effect of Local Anesthetics on Ca2+ Transport.- D. Adrenergic Blocking Agents.- E. Effect of Atebrine, Amytal, Chlorpromazine, Reserpine, Imipramine, and Prenylamine.- F. Effect of Ryanodine.- G. Miscellaneous Inhibitors of Ca2+ Transport.- XIII. Ca2+ Transport in Muscle Disease.- References.- 4: The Isolation of the Surface Membranes of Animal Cells: A Survey.- I. Introduction.- II. General Comments on the Isolation.- A. Morphology.- B. Membrane Markers.- C. Storage of Membranes.- III. Isolation of Surface Membranes.- D. Tissue Culture Cells.- E. Ehrlich Ascites Carcinoma Cells.- F. Toad Bladder Epithelium.- G. Muscle Cells.- H. Nerve-Ending Membranes and Synaptic Vesicles.- I. Fat Cells.- J. Avian Myeloblasts.- K. Amoebae.- L. Microvillus Membranes.- IV. Conclusions.- References.