Main description:

This book provides a comprehensive examination of the newest biopharmaceutical drugs. Among the drugs discussed are ones in the categories of monoclonal antibodies for in-vivo use, cytokines, growth factors, enzymes, immunomodulators, thrombolytics, and immonotherapies including vaccines. Additionally, the volume examines new and emerging technologies, and contains a review of the Human Genome Project.

Contents:

Biopharmaceutical Drug Design and Development
Second Edition

1. Biotechnology: 2005 and Beyond
2. Human Genome Project
3. Bioinformatics
4. DNA Microarrays in Drug Discovery and Development
5. Microarray Technology Using Proteins, Cells, and Tissues
6. Pharmacogenetic Issues in Biopharmaceutical Drug Development
7. Transgenics
8. Therapeutic Gene Delivery
9. Stem Cells
10. Nucleic Acid Based Therapeutics
11. Therapeutic Strategies Targeting the Innate Immune Response
12. Pharmacogenetics in the Clinic
13. Molecular Modeling: Considerations for the Design of
Pharmaceuticals and Biopharmaceuticals
14. Macromolecular Drug Delivery
15. Changes in Biologic Drug Approval at FDA
16. Follow On Protein Products: The Age of Biogenerics?