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Published December, 2011
By F. Melchers, M. Potter and M. Weigert
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
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At the end of the last century and the beginning of this century, the prob lems of immunity in lower vertebrates and the influence of environmental temperature attracted attention for the first time (ERNST, 1890;

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Published December, 2011
By Peter Sarnow
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
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Published December, 2011
By Steinunn Baekkeskov and Bruno Hansen
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
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The first volume, CTMI 156, (see page VI for contents) provided data on the animal models and experimental approaches currently employed to evaluate both the autoimmune and virologic factors contributing to the causation and patho genesis of diabetes.

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To translate this newly acquired knowledge into clinical practice, clinical trials have also been performed to evaluate numerous new therapeutic drugs.

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Published December, 2011
By Garnett Kelsoe and Martin Flajnik
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
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Discovery of the mechanism for V(D)J hypermutation remains a basic goal of immunology despite the best efforts of many labo ratories. Our work has not only shown us what the mutator is not, it has also, like an artist's preliminary sketch, defined the questions and experiments we must face without diminishing the potential for new biology.

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Published December, 2011
By Arthur E. Frankel
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
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PASTAN , and J. ROBERTUS Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 3 Intracellular Processing - Cleavage and Reduction . . . . . . 1 Cytosolic Activity . . . , diphtheria toxin, Pseudomonas exotoxin and ricin) are among the most toxic substances known.

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Published December, 2011
By R. Jaenisch and T. Graf
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
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General aspects of nucleic acid uptake by mammalian cells have been the subject of several reviews during the last few years (PAGANO, 1970;

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