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Each control operation is mediated by a pair of complementary genetic elements (hereafter called "control cell"): a control gene which produces a l control (or regulator) protein and a control site which is the target for the regulator protein. Negative control means that the control protein (repressor) prevents gene expression.

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Two kinds of antigenic variation occur in influenza viruses, antigenic drift and major antigenic shifts; Antigenic drift, which involves gradual changes in the surface antigens of influenza virus, is thought to result from the selection by an immune popula tion of mutant virus particles with altered antigenic determinants.

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Published November, 2011
By Fritz Melchers and Michael Potter
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
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Although separation techniques have been used in a variety of cellular systems, they have been particularly useful in the study of reticuloendothelial cells and primarily in the study of cells partici pating in the immune responses.

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Published November, 2011
By Barry T. Rouse
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
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Although upstaged by the tragic appearance of the human immunodeficiency virus, herpes simplex viruses (HSV) types 1 and 2 continue to be major human pathogens against which we lack acceptable vaccines or other means of immunological control.

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