Published July, 2006
By Tasuku Honjo, Fritz Melchers and T. Honjo
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
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Published June, 2006
By Walter Doerfler, Petra Bohm and Petra Boehm
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
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Availability: Available

It has become apparent that the genomes of many organisms are characterized by unique patterns of DNA methylation which can differ from genome segment to genome segment and cell type to cell type.

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Published May, 2006
By William M. Shafer, William Shafer and William Schaffer
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
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This volume of CTMI, entitled Antimicrobial Peptides and Human Disease, is dedicated to the role of antimicrobial peptides (AMPs) in the innate host defense system of homo sapiens.

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Published May, 2006
By Polly Roy
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
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A review of our current understanding of Reoviridae entry, disassembly/assembly and egress in addition to updating high resolution structures of virus proteins and capsids from three different genera of the family.

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Published May, 2006
By John L. Casey
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
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Hepatitis delta virus (HDV), which causes severe acute and chronic liver disease, was discovered nearly 30 years ago following the detection of a novel antigen-antibody system in hepatitis B virus carriers.

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Published April, 2006
By Peter E. Lipsky and Andreas Radbruch
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
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Availability: Available

In addition, there are in?uences that are extrinsic to potentially auto-reactive lymphocytes, including the function of regulatory cells, d- ferentiation state of antigen-presenting cells, availability of self-antigen, the cytokine and chemokine milieu, as well as the traf?cking patterns involved in generating productive immune interactions.

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Published March, 2006
By Thomas E. Lane
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
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Chemokines represent a family of over 40 small proteins that, for the most part, are secreted into the environment and function by binding to G protein-coupled receptors (GPCRs) that are expressed on numerous different cell types.

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Published February, 2006
By Robert N. Eisenman
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Current Topics in Microbiology and Immunology
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Availability: Available

Scientists often look askance at their colleagues whose research appears too strongly focused on a single gene or gene product. These rearrangements (including chromosomal translocation, viral integration, and gene ampli?cation) act to uncouple expression of the myc family genes from their normal physiological regulators.

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