Published March, 2012
By Keith DiPetrillo
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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As two of the leading causes of death worldwide, heart disease and stroke represent a clear target for genomic research aimed at deciphering the genes and cellular pathways that underlie cardiovascular disease and creating improved therapies.

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Published March, 2012
By Keith R. Fox
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

Within the last 10 years, it has also become apparent that the familiar DNA duplex is not the only structure that can be targeted by DNA-binding ligands and there has been increased interest in triplex and quadruplex structures as drug targets, as well as protein- DNA complexes, such as those with nucleosomes or topoisomerases.

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Published March, 2012
By Marina Cretich and Marcella Chiari
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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In this book, experts provide a cutting-edge view of peptide array technology, its applications, and technical issues. The book aims to serve scientists with its insights and novel solutions in peptide array technology in order to advance this vital field.

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Published March, 2012
By Robert Grutzmann and Christian Pilarsky
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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This is a fundamental yet comprehensive guidebook for researchers in the field of cancer gene profiling, as well as for those individuals in the area of biomedical/translational research. It examines the world of cancer gene profiling in light of new advances.

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Published March, 2012
By Preston B. Rich and Christelle Douillet
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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This second edition details the newest and most innovative techniques in this rapidly expanding field. It provides methods and assays that can be adapted and used in most specialties of biomedical and biotechnological fields.

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Published March, 2012
By Tian Jin and Dale Hereld
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Fundamental to the development and vital functions of organisms, the migration of motile cells due to the detection of shallow gradients of specific chemical signals in their environments, or chemotaxis, can be clearly seen as a major force in cell biology.

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Published March, 2012
By Duncan J. Clarke
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Due to their importance to cell biology, DNA topology-altering enzymes, collectively DNA topoisomerases and gyrases, have been studied thoroughly from a biochemical perspective, yet the expansion of research at the molecular and cellular levels continues to show a great deal of promise.

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Published March, 2012
By Edgar Jacoby
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Chemogenomics aims toward the systematic identification of small molecules that interact with the products of the genome and modulate their biological function.

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Published March, 2012
By Philippe Collas
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

In this book, researchers deeply involved in the development and improvement of chromatin immunoprecipitation assays (ChIP) provide cutting-edge protocols devoted to the most recent progress in ChIP and related subjects.

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Published March, 2012
By Mohamed M. Abdelhaleem
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

This volume examines methods for the production and purification of helicases from different species. It also offers detailed studies of helicase activities, including NTP binding and hydrolysis, and translocation along nucleic acid substrates.

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