Published November, 2010
By Tuan Vo-Dinh
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

Among the highlights are techniques for the in vivo tracking of biochemical processes using fluorescent molecular probes and nanosensors, and the exploration of biochemical processes and submicroscopic structures of living cells at unprecedented resolutions using near-field optics.

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Published November, 2010
By Wieland Kiess, Dieter Korholz and Dieter Koerholz
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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The immune system is a complex network in which different cell types and soluble factors interact to efficiently eliminate various kinds of microorganisms as well as aberrant cell clones.

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Published November, 2010
By Piet Herdewijn
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

Among the protocol highlights are a novel two-step process that yields a high purity, less costly, DNA, the synthesis of phosphorothioates using new sulfur transfer agents, the synthesis of LNA, peptide conjugation methods to improve cellular delivery and cell-specific targeting, and triple helix formation.

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Published November, 2010
By Jonatha M. Gott
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

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Published November, 2010
By A. Kristina Downing
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

Staying with the idea of isotopic labeling, Chapter 3 describes methods for perdeuteration and site-specific protonation and is the first of several chapters in the book that is relevant to studies of higher molecular weight systems.

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Published November, 2010
By Cam Patterson and Douglas M. Cyr
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

State-of-the-art and user-friendly, Ubiquitin-Proteasome Protocols offers novice and experienced bench scientists alike a thorough compendium of readily reproducible techniques that will accelerate discovery, enhance productivity, and permit manipulation of the system for varied research purposes.

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Published November, 2010
By Pierre Thibault and Susumu Honda
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Published November, 2010
By Jonathan M. Gibbins and Martyn P. Mahaut-Smith
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

Part I of Volume 1, Platelets and Megakaryocytes: Functional Assays, describes many well established approaches to the study of platelet function, including aggregometry, secretion, arachidonic acid metabolism, procoagulant responses, pla- let adhesion under static or flow conditions, flow cytometry, and production of microparticles.

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Published November, 2010
By Peter Bross and Niels Gregersen
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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In addition, deficiencies of proteins that are engaged in assisting and supervising protein folding (protein quality control) may impair the folding of many other proteins, resulting in pathological phenotypes.

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Published November, 2010
By Daniele D'Ambrosio and Francesco Sinigaglia
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

The disparity between the large number of chemokines and that smaller number of receptors is balanced by the promiscuity in ligand-receptor interactions, with multiple chemokines binding to the same receptor and several chemokines binding to more than one receptor.

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