Published October, 2008
By Novartis Foundation, Gregory R. Bock and Jamie A. Goode
Publisher: John Wiley & Sons Ltd
Series: Novartis Foundation Symposia
Rating:
Availability: Not available (reason unspecified)

This book covers basic issues concerning the nature of the worldwide health problem posed by cigarette smoking and explores the psychodynamics of cigarette addiction. The basic pharmacology and biochemistry of nicotine and its effect on the brain are reviewed here.

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Published October, 2008
By Novartis Foundation, Gregory R. Bock and Jamie A. Goode
Publisher: John Wiley & Sons Ltd
Series: Novartis Foundation Symposia
Rating:
Availability: Not available (reason unspecified)

Over the past five years, there has been dramatic progress in unravelling the cellular circuitry involved in cardiac failure, as well as in normal cardiac growth, development and apoptosis. These studies have revealed new and unanticipated therapeutic targets in the heart.

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Published October, 2008
By Novartis Foundation
Publisher: John Wiley & Sons Ltd
Series: Novartis Foundation Symposia
Rating:
Availability: Not available (reason unspecified)

Cl- absorption and HCO3- secretion are intimately associated processes vital to epithelial function, itself a key physiological activity. Until recently the transporters responsible remained obscure, but a breakthrough occurred with the discovery of the SLC26 transporters family.

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Published October, 2008
By Novartis Foundation, Derek J. Chadwick and Jamie A. Goode
Publisher: John Wiley & Sons Ltd
Series: Novartis Foundation Symposia
Rating:
Availability: Not available (reason unspecified)

ATP, the intracellular energy source, is also an extremely important cell-cell signalling molecule for a wide variety of cells across evolutionarily diverse organisms. The extracellular biochemistry of ATP and its derivatives is complex, and the multiple membrane receptors that it activates are linked to many intracellular signalling systems.

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Published October, 2008
By Novartis Foundation, Gregory R. Bock and Jamie A. Goode
Publisher: John Wiley & Sons Ltd
Series: Novartis Foundation Symposia
Rating:
Availability: Not available (reason unspecified)

For the first time contributions are brought together from a multidisciplinary team of biologists and computer scientists to explore the issues related to immune function. This will help biologists apply new computer scientific methods to immunological research. The book considers practical applications (e.g.

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Published October, 2008
By Novartis Foundation
Publisher: John Wiley & Sons Ltd (Wiley–Blackwell)
Series: Novartis Foundation Symposia
Rating:
Availability: Not available (reason unspecified)

This book draws together contributions from cell and developmental biologists, structural biologists, geneticists and clinical scientists aimed at a better understanding of the cellular and molecular basis of these diseases.

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Published October, 2008
By Novartis Foundation
Publisher: John Wiley & Sons Ltd (Wiley–Blackwell)
Series: Novartis Foundation Symposia
Rating:
Availability: Not available (reason unspecified)

The object of this book is to gather together workers in the fields of epilepsy, those concerned with the basic science of resistance and the blood–brain barrier, and those with clinical experience of drug resistance in cancer, with a view to stimulating further work on drug resistance in epilepsy.

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Published October, 2008
By Novartis Foundation
Publisher: John Wiley & Sons Ltd (Wiley–Blackwell)
Series: Novartis Foundation Symposia
Rating:
Availability: Not available (reason unspecified)

This important book covers the structure and molecular biology of small round structured viruses (SSRVs) such as caliciviruses and astroviruses, and the basic pathology of infection. It provides readers with the knowledge needed to make progress in the prevention and treatment of these infections.

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Published October, 2008
By Novartis Foundation
Publisher: John Wiley & Sons Ltd (Wiley–Blackwell)
Series: Novartis Foundation Symposia
Rating:
Availability: Not available (reason unspecified)

Social and medical developments have recently led to a dramatic increase in life expectancy. This has inspired the study of organismic changes associated with healthy ageing, in particular the erosion of homeostatic capabilities in multiple endocrine systems.

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Published October, 2008
By Novartis Foundation
Publisher: John Wiley & Sons Ltd (Wiley–Blackwell)
Series: Novartis Foundation Symposia
Rating:
Availability: Not available (reason unspecified)

Many human diseases such as cancer, diabetes and neural disorders arise from the malfunction of signaling components. This is frequently due to alterations of multiple components of an integrated signaling network.

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