Main description:

Cancer Stem Cells, Volume 141 in the Advances in Cancer Research series, presents the latest release in this ongoing, well-regarded serial that provides invaluable information on the exciting and fast-moving field of cancer research. Topics covered in this new release include SIX-EYA-DACH network control of cancer stem cell properties, Dormancy and the cancer cell niche, Clonal hematopoiesis: A hematopoietic stem cell disorder of aging, Stringent assays to study human breast cancer stem cells, Regulation of breast cancer stem cell specification and maintenance by hypoxia-inducible factors, Cancer stem cells in breast and prostate: fact or fiction, and much more.

Contents:

1. Regulation of cancer stem cell properties by SIX1, a member of the PAX-SIX-EYA-DACH network Tami J. Kingsbury, MinJung Kim and Curt I. Civin 2. Dormancy and cancer stem cells: An enigma for cancer therapeutic targeting Sarmistha Talukdar, Praveen Bhoopathi, Luni Emdad, Swadesh Das, Devanand Sarkar and Paul B. Fisher 3. Clonal hematopoiesis: Pre-cancer PLUS Alexander J. Silver and Siddhartha Jaiswal 4. Assays for functionally defined normal and malignant mammary stem cells Syed M. Musheer Aalam, Philip A. Beer and Nagarajan Kannan 5. Hypoxia-inducible factors promote breast cancer stem cell specification and maintenance in response to hypoxia or cytotoxic chemotherapy Lisha Xiang and Gregg L. Semenza 6. Exploiting epigenetically mediated changes: Acute myeloid leukemia, leukemia stem cells and the bone marrow microenvironment Aksinija A. Kogan, Rena G. Lapidus, Maria R. Baer and Feyruz V. Rassool