Published November, 2014
By Rodrick Wallace, Deborah Wallace and Dr Rodrick Wallace
Publisher: Springer (Springer-Verlag New York Inc.)
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Gene Expression and its Discontents examines a class of probability models describing how epigenetic context affects gene expression and organismal development, using the asymptotic limit theorems of information theory in a highly formal manner.

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Published November, 2014
By Gabriel Waksman
Publisher: Springer (Springer-Verlag New York Inc.)
Series: Protein Reviews
Rating: 1.00
Availability: Available

Gabriel Waksman Institute of Structural Molecular Biology, Birkbeck and University College London, Malet Street, London WC1E 7HX, United Kingdom Address for correspondence: Professor Gabriel Waksman Institute of Structural Molecular Biology Birkbeck and University College London Malet Street London WC1E 7H United Kingdom Email: g.

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Published November, 2014
By Vijay S. Tonk and Herman E. Wyandt
Publisher: Springer
Rating:
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Published November, 2014
By Simon M. Lin and Jennifer S Shoemaker
Publisher: Springer (Springer-Verlag New York Inc.)
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Availability: Available

As studies using microarray technology have evolved, so have the data analysis methods used to analyze these experiments. Previous books in this series focused on classification (Volume I), pattern recognition (Volume II), and quality control issues (Volume III). In this volume, four lung cancer data sets are the focus of analysis.

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Published November, 2014
By Guy Faguet
Publisher: Springer
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Based on 30 years of clinical and research experience, backed by a careful assessment of four decades of published data, Dr. Faguet documented in The War on Cancer (Springer 2005), early advances in cancer treatment and patient survival that soon stalled.

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Published November, 2014
By Trygve O. Tollefsbol and Trygve Tollefsbol
Publisher: Springer (Springer-Verlag New York Inc.)
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Availability: Available

Many epigenetic alterations can have an impact on aging processes such as stem cell aging, control of telomerase, modifications of telomeres, and epigenetic drift can impact the aging process as evident in the recent studies of aging monozygotic twins.Numerous age-related diseases are affected by epigenetic mechanisms.

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Published November, 2014
By Bernhard Haendler, D. Mumberg and Otmar D Wiestler
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Ernst Schering Foundation Symposium Proceedings
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Availability: Available

Cancer stem cells have originally been identified in leukemia and later in several solid tumor types. Current treatments might largely spare cancer stem cells. This book looks at recent developments in the field of cancer stem cells and the possible impact for the identification of novel treatment paradigms for cancer.

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Published November, 2014
By Gabriel D. Dakubo
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
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In spite of the enormous complexity of the nuclear genome, which we now fully appreciate after completion of the human genome project, the efforts of cancer researchers are commendable in terms of the tremendous gains made in unraveling the numerous genetic changes in cancer.

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Published November, 2014
By Gerard P. Zambetti
Publisher: Springer (Springer-Verlag New York Inc.)
Series: Protein Reviews
Rating: 1.00
Availability: Available

The current year (2004) marks the Silver Anniversary of the discovery of the p53 tumor suppressor. Fueling the concept of p53 acting as a transforming factor, p53 expression was markedly elevated in various transformed and tumorigenic cell lines when compared to normal cells.

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Published November, 2014
By Trygve O. Tollefsbol
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Several new tools for the analysis of biological aging have been introduced recently, and this volume provides methods and protocols for these new techniques in addition to its coverage of established procedures. Researchers seeking new technology and techniques will find this volume of tremendous benefit as they move towards new directions.

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