Published January, 2014
By David A. Frank
Publisher: Springer (Springer-Verlag New York Inc.)
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Availability: Available

In recent years, increasing evidence has suggested that abnormal activation of signaling pathways is a critical event in cancer pathogenesis. Thus, understanding the mechanisms by which signaling pathways become subverted in a cancer cell can provide insight into critical events in cancer pathogenesis.

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Published January, 2014
By Isabelle Mercier, Jean Francois Jasmin and Michael P. Lisanti
Publisher: Springer (Springer-Verlag New York Inc.)
Series: Current Cancer Research
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Availability: Available

Caveolins are important structural proteins of Caveolae, small invaginations of the membrane. In this volume, we will mainly focus on the importance of Caveolin-1 in breast, prostate, lung, skin, colon, pancreatic and brain cancers with also a mention of the novel role of Caveolin-3 in breast cancer.

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Published January, 2014
By Paul Trainor
Publisher: Elsevier (Academic Press Inc)
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Summarizes discoveries of historical significance and provides analyses of the evolution of neural crest cells, their contribution to embryo development, and their roles in disease. This title provides comprehensive synthesis of the current knowledge of neural crest cells. It covers the evolution and development of neural crest cells.

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Published January, 2014
By Wyatt Travis Clark
Publisher: Springer (Springer International Publishing AG)
Series: SpringerBriefs in Computer Science
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The development of effective methods for the prediction of ontological annotations is an important goal in computational biology, yet evaluating their performance is difficult due to problems caused by the structure of biomedical ontologies and incomplete annotations of genes.

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Published January, 2014
By Brent L. Fogel
Publisher: Elsevier (Elsevier - Health Sciences Division)
Series: The Clinics: Radiology
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Features a review of clinical neurogenetics as it pertains to the following disorders: Huntington Disease; Autism/ASD; Fragile X Tremor Ataxia Syndrome (FXTAS); Lysosomal Storage Diseases; Psychiatric Disorders; Dominant Spinocerebellar Ataxias; Metabolic Disorders; Friedreich Ataxia; ALS; Dementia; Neuromuscular Disorders; Epilepsy; and Dystonia.

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Published January, 2014
By V. V. Kushev
Publisher: Springer (Springer-Verlag New York Inc.)
Series: Studies in Soviet Science
Rating:
Availability: Available

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Published January, 2014
By Peter A. Jones and Michael Lubbert
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Rating:
Availability: Available

The growing knowledge about disturbances of epigenetic gene regulation in hematopoietic stem cell disorders is now being translated into treatment approaches that target the epigenetic defects pharmacologically.

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Published January, 2014
By Robert J. Arceci, Graham Dellaire and Jason N. Berman
Publisher: Elsevier (Academic Press Inc)
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Availability: Available

Addresses how technological advances in genomics are shaping how we diagnose and treat cancer. This book concludes with "Future Directions", examining the next great challenges to face the field of cancer genomics, namely the contribution of non-coding RNAs to disease pathogenesis and the interaction of the human genome with the environment.

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Published January, 2014
By Alberto Fuente and Alberto de la Fuente
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
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Availability: Available

This book presents recent methods for Systems Genetics (SG) data analysis, applying them to a suite of simulated SG benchmark datasets. Each of the chapter authors received the same datasets to evaluate the performance of their method to better understand which algorithms are most useful for obtaining reliable models from SG datasets.

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Published January, 2014
By Marion Becker, Ed Louis, Edward J Louis and Marion M Becker
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
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Availability: Available

The mosaic nature of this collection and the everchanging perspectives reflect the nature of subtelomeres themselves.Unlike the core of most genomes, which are conserved and stable over time, subtelomeres are dynamic and polymorphic, so much so that generally no two individuals look alike in these regions.

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