Published March, 2012
By Keith DiPetrillo
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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As two of the leading causes of death worldwide, heart disease and stroke represent a clear target for genomic research aimed at deciphering the genes and cellular pathways that underlie cardiovascular disease and creating improved therapies.

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Published March, 2012
By John F. Atkins and Raymond F. Gesteland
Publisher: Springer (Springer-Verlag New York Inc.)
Series: Nucleic Acids and Molecular Biology
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Availability: Available

These results showed that the code has been c- served during evolution and strongly suggested that the code appeared very early during biological evolution, that all forms of life on earth descended from a c- mon ancestor, and thus that all forms of life on this planet are related to one another.

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Published March, 2012
By Keith R. Fox
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

Within the last 10 years, it has also become apparent that the familiar DNA duplex is not the only structure that can be targeted by DNA-binding ligands and there has been increased interest in triplex and quadruplex structures as drug targets, as well as protein- DNA complexes, such as those with nucleosomes or topoisomerases.

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Published March, 2012
By Edgar Jacoby
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Chemogenomics aims toward the systematic identification of small molecules that interact with the products of the genome and modulate their biological function.

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Published March, 2012
By Philippe Collas
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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In this book, researchers deeply involved in the development and improvement of chromatin immunoprecipitation assays (ChIP) provide cutting-edge protocols devoted to the most recent progress in ChIP and related subjects.

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Published March, 2012
By Bo Peng, Marek Kimmel, Christopher I. Amos and B Peng
Publisher: John Wiley & Sons Ltd (John Wiley & Sons Inc)
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Availability: Available

The rapid increase of the power of personal computers has led to the use of serious simulation programs such as easy POP in genetic studies. This book summarizes recent advances in forward-time simulation methods and demonstrates their applications in population genetics and genetic epidemiology.

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Published March, 2012
By A. Kuliev and Yury Verlinsky
Publisher: Springer (Springer-Verlag New York Inc.)
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Published March, 2012
By Claes Lundsteen and Jim Piper
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
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Availability: Available

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Published March, 2012
By En Li and Susan M. Gasser
Publisher: Springer (Springer Basel)
Series: Progress in Drug Research
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Availability: Available

Included are descriptions of epigenetic controls over gene expression, the post-transcriptional silencing of genes by RNA interference (RNAi) and microRNAs, as well as new findings from stem cell research which are relevant to pharmacological applications.

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Published March, 2012
By Bart De Strooper
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Research and Perspectives in Neurosciences
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Availability: Available

The discovery of microRNAs has revealed an additional level of fine tuning of the genome and how genes are used again and again in different combinations to generate the complexity that underlies for instance the brain. This book examines this field.

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