Published March, 2012
By Heinz Peter Nasheuer
Publisher: Springer
Series: Subcellular Biochemistry
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Availability: Available

In this hypothesis, these rare genetic events represent rate-limiting 'bottlenecks' in the clonal evolution of a cancer, and pre-cancerous cells can evolve into neoplastic cells through the acquisition of somatic mutations.This book is written by international leading scientists in the field of genome stability.

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Published March, 2012
By Tamas Balla, Matthias Wymann and John D. York
Publisher: Springer
Series: Subcellular Biochemistry
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Availability: Available

Phosphoinositides play a major role in cellular signaling and membrane organization.

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Published March, 2012
By Henry F. Epstein
Publisher: Springer (Springer-Verlag New York Inc.)
Series: Advances in Experimental Medicine and Biology
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The present volume contains the edited transcript of a collo quium sponsored by the Muscular Dystrophy Association and held at Mountain Shadows Inn, Scottsdale, Arizona, December 14-16, 1981.

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Published February, 2012
By Carlos Lopez-Larrea, Antonio Lopez Vazquez and Beatriz Suarez Alvarez
Publisher: Springer (Springer-Verlag New York Inc.)
Series: Advances in Experimental Medicine and Biology
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In the beginning of this century, we are witnessing with great expectations the emergence of a new field of medicine related to the arrival of a new player on the scene: "stem cells" and their potential use in regenerative medicine.

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Published February, 2012
By J.F. Crow and Jon A. Wolff
Publisher: Springer (Springer-Verlag New York Inc.)
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Availability: Available

During the first half century of genetics, coinciding with the first half of this cen tury, geneticists dreamt of the repair of genetic disease by altering or replacing defective genes.

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Published February, 2012
By M. Sharon Stack and David A. Fishman
Publisher: Springer (Springer-Verlag New York Inc.)
Series: Cancer Treatment and Research
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Availability: Available

Ovarian carcinoma continues to be responsible for more deaths than all other gynecologic malignancies combined, due to a continued inability to achieve detection of early (rather than advanced) stage disease and the lack of effective tumor-specific therapeutics.

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Published February, 2012
By Piri Welcsh
Publisher: Springer (Springer-Verlag New York Inc.)
Series: Cancer Genetics
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Availability: Available

This volume will explore the latest findings in research into the genetics of breast and reproductive cancers, covering the epidemiological aspects of these cancers, their etiology, the effect of environment on genes and cancer etiology, and how research in this area can lead to development of preventative measures and treatments.

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Published February, 2012
By Matthew Davies, Shoba Ranganathan and Darren D.R. Flower
Publisher: Springer (Springer-Verlag New York Inc.)
Series: Immunomics Reviews:
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Availability: Available

This fourth volume of a series is dedicated to advances in immunomics. The focus is on systemic and integrative approaches in basic and clinical immunology, immunoinformatics, and immunologically relevant instrumentation and high-throughput screening methods.

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Published February, 2012
By Anton A. Komar
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Chapters address the impact of SNPs on phenotype, examine SNP databases, look at methods that have been applied for SNP bioinformatics discovery and analysis, and discuss advanced experimental approaches used for SNP detection.

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Published February, 2012
By Eyal Raz
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Principles and Practice
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Availability: Available

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