Published May, 2011
By Otto-Wilhelm Merten and Mohamed Al-Rubeai
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

The huge potential for gene therapy to cure a wide range of diseases has led to high expectations and a great increase in research efforts in this area, particularly in the study of delivery via viral vectors, widely considered to be more efficient than DNA transfection.

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Published May, 2011
By Scott Q. Harper
Publisher: Springer (Humana Press Inc.)
Series: Neuromethods
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Non-coding, inhibitory microRNAs have emerged as important modulators of cellular gene expression, through a process called RNA interference (RNAi).

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Published May, 2011
By Timothy R. Hughes
Publisher: Springer
Series: Subcellular Biochemistry
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Written from a genome-based perspective, this volume provides an objective overview of transcription factor biochemistry. Topics include known transcription factor classes, origins and evolution of transcription factor types, and mechanisms of interaction with chromatin.

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Published May, 2011
By Margarida D. Amaral and Karl Kunzelmann
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Despite the many milestones in cystic fibrosis (CF) research, progress toward curing the disease has been slow, and it is increasingly difficult to grasp and use the already wide and still growing range of diverse methods currently employed to study CF so as to understand it in its multidisciplinary nature.

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Published May, 2011
By Steve Horvath
Publisher: Springer (Springer-Verlag New York Inc.)
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High-throughput measurements of gene expression and genetic marker data facilitate systems biologic and systems genetic data analysis strategies. Gene co-expression networks have been used to study a variety of biological systems, bridging the gap from individual genes to biologically or clinically important emergent phenotypes.

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Published April, 2011
By Kevin M. Sweet and Ron C. Michaelis
Publisher: Springer
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In the coming decade, the focus of medicine will shift from a disease-oriented approach, where the physician prescribes according to the disease the patient has, to a personalized approach, in which the physician first considers the patient's individual biochemistry before prescribing a treatment.

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Published April, 2011
By Giorgio M. Innocenti, Janette Atkinson, Dr., Dr. Oliver Braddick and Oliver Braddick
Publisher: Elsevier (Elsevier Science Ltd)
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Links findings on the structural development of the human brain, the expression of genes in behavioural and cognitive phenotypes, environmental effects on brain development, and developmental processes in perception, action, attention, cognitive control, social cognition, and language.

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Published April, 2011
By Gyula Hadlaczky
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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The rapid progression of genetics and molecular biology has turned chromosomal engineering from science fiction to reality, with the successful production of transgenic animals with engineered chromosomes and chromosomes developed for pharmaceutical protein production which are now ready for the medical industry.

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Published April, 2011
By Ira S. Cohen and Glenn R. Gaudette
Publisher: Springer (Humana Press Inc.)
Series: Stem Cell Biology and Regenerative Medicine
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Here, an array of talented researchers covers our current state of knowledge in this exciting field. Four sections cover applications of stem cell techniques to mechanical regeneration, electrical regeneration, cardiac tissues and in vivo stem cell therapies.

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Published April, 2011
By Felix Bronner, Helmtrud I. Roach and Richard O.C. Oreffo
Publisher: Springer (Springer London Ltd)
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Availability: Available

Epigenetic Aspects of Chronic Diseases assembles in comprehensive form what is known about the role of epigenetics in chronic disease development.

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