Published November, 2010
By Alexander Serganov
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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The discovery of RNA interference and multiple bacterial regulatory RNAs caused a shift from the perception of proteins as the predominant regulators of gene expression to the acknowledgement of the importance of RNAs in many regulatory circuits.

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Published November, 2010
By Michael Zachariou
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Thirty-eight years after its introduction, affinity chromatography remains a key tool in the armory of separation techniques available to separation and interaction scientists.

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Published November, 2010
By William J. Murphy
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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The past decade has seen the emergence of a new field of scientific inquiry at the intersection of phylogenetics and genomics: phylogenomics.

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Published November, 2010
By Jang B. Rampal
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Coverage includes applications in DNA, peptide, antibody and carbohydrate microarraying, oligonucleotide microarrays generated from hydrolysis PCR probe sequences, microarray platforms in clinical practice, and screening of cDNA libraries on glass slide microarrays.

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Published November, 2010
By Elizabeth H. Chen
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Divided into two convenient parts, the volume begins with nine overviews which describe different cell fusion events in models from yeast to mammals, and it continues with thirteen chapters illustrating commonly used methods to assay cell fusion in particular systems.

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Published November, 2010
By Federico Innocenti
Publisher: Springer (Humana Press Inc.)
Series: Cancer Drug Discovery and Development
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Availability: Available

Genomics and Pharmacogenomics in Anticancer Drug Development and Clinical Response provides the most comprehensive body of knowledge available on the role of genetic and genomic variation in the individualization of drug therapies in cancer patients.

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Published November, 2010
By Mark Giezen and Mark van der Giezen
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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In this updated volume, experts from around the world provide the latest protocols for isolating different organelles and the localization of particular proteins using a variety of methods such as light, confocal, and electron microscopy. Emphasis is placed on protein targeting of cellular compartments in both prokaryotic and eukaryotic systems.

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Published November, 2010
By Iain J. McEwan and Iain J. McEwan, PhD
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Acting principally to control patterns of gene expression, nuclear receptors play vital roles during embryonic development and in the regulation of metabolic and reproductive functions in adult life, which proves this superfamily of ligand-activated transcription factors to be a crucial part of biological life.

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Published November, 2010
By Robert Feil and Daniel Metzger
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Handbook of Experimental Pharmacology
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With contributions by numerous experts

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Published November, 2010
By Simone Mocellin
Publisher: Springer (Springer-Verlag New York Inc.)
Series: Advances in Experimental Medicine and Biology
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Availability: Available

Given the revolutionary implications that the use of this technology might have in the clinical management of cancer patients, the principles of DNA array-based tumor gene profiling must be clearly understood for the data to be correctly interpreted and appreciated.

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