Published November, 2010
By Joyce C. Solheim
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
Rating:
Availability: Available

Antigen processing and presentation, as a field, explores a broad range of protein interactions and functions, both intracellular (in the cytoplasm and in the endoplasmic reticulum) and at the cell surface (between T cells and MHC molecules).

---

Published November, 2010
By Mark W. Saltzman, Hong Shen and Janet L. Brandsma
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Medicine
Rating:
Availability: Available

In the early 1990s, almost 200 yr after Edward Jenner demonstrated the effectiveness of the smallpox vaccine, a new paradigm for vaccination emerged.

---

Published November, 2010
By Wieland Kiess, Dieter Korholz and Dieter Koerholz
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
Rating:
Availability: Available

The immune system is a complex network in which different cell types and soluble factors interact to efficiently eliminate various kinds of microorganisms as well as aberrant cell clones.

---

Published November, 2010
By W. Scott Champney
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Medicine
Rating:
Availability: Available

This book examines specific techniques which can be used to explore new drug targets and the effectiveness of new antibiotics.

---

Published November, 2010
By Timothy N.C. Wells, Amanda E.I. Proudfoot and Christine Power
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
Rating:
Availability: Available

What has emerged over the years is that most chemokine receptors bind several distinct ligands, and indeed the majority of chemokines are able to bind to multiple chemokine receptors, explaining to some extent the apparent disparity in the numbers of chemokines and rec- tors.

---

Published November, 2010
By Joanna B. Wilson, Gerhard May and Gerhard H. W. May
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
Rating:
Availability: Available

The discovery of Epstein-Barr virus (EBV) by Epstein, Achong, and Barr, reported in 1964 (Lancet 1:702-703), was stimulated by Denis Burkitt's rec- nition of a novel African childhood lymphoma and his postulation that an infectious agent was involved in the tumor's etiology (Nature194:232-234, 1962).

---

Published November, 2010
By Walter A. Hall
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
Rating:
Availability: Available

Immunotoxins represent a new class of human therapeutics that have widespread applications and a potential that has not yet been fully recognized since they were first conceived of by Paul Ehrlich in 1906.

---

Published November, 2010
By Paul G. Winyard, Derek A. Willoughby and Paul Winyard
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
Rating:
Availability: Available

Thus, a proper understanding of the inflammatory basis may provide clues to new therap- tic targets not only in classical inflammatory diseases, but atherosclerosis, cancer, and ischemic heart disease as well.

---

Published November, 2010
By Daniel J. J. Carr
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Medicine
Rating:
Availability: Available

Offers a compendium of optimized methods to measure type I interferon efficacy as an antiproliferative or an antiviral agent. In this title, advanced techniques range from the simple to the highly complex and serve to illuminate the signaling cascades and the activation of enzymatic pathways prompted by interferon.

---

Published November, 2010
By Benny K.C. Lo and Benny K. C. Lo
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
Rating:
Availability: Available

Despite this setback, advances in recombinant DNA techniques over the last 15-20 years have empowered the engineering of recombinant antibodies with desired characteristics, including properties to avoid HAMA.

---