Main description:

Chronopharmaceutics covers the fundamentals of the various aspects of chronopharmaceutics in the fields of chronobiology, chronogenetics, chronophysiology, chronopathology, chronopharmacology, chronotherapeutics, chronotoxicology and chronobiotics, and chronopharmaceutical drug delivery research. It discusses different and specific controlled-release systems that are triggered by electrics, diffusion, and chemical-activation and concludes with a description of the regulatory issues along with formulation and manufacturing.

Contents:

PREFACE. ACKNOWLEDGMENTS. CONTRIBUTORS. ABBREVATION LIST. INTRODUCTION: TIME, DIAGNOSTICS, AND THERAPEUTICS-BEYOND CIRCADIAN MARKER RHYTHM-GUIDED TREATMENT ( Franz Halberg, Germaine Corne lissen, and Othild Schwartzkopff ). 1 OVERVIEW OF CHRONOPHARMACEUTICS ( Bi-Botti C. Youan ). 2 CHRONOGENETICS ( Franck Delaunay ). 3 CHRONOPHARMACOKINETICS ( Bernard Bruguerolle ). 4 CHEMICAL OSCILLATOR SYSTEMS FOR CHRONOTHERAPY ( Steven A. Giannos ). 5 DIFFUCAPS TECHNOLOGY FOR CONTROLLED RELEASE DRUG DELIVERY ( Gopi Venkatesh ). 6 CHRONOTOPICt TECHNOLOGY (M . E. Sangalli, A. Maroni, L. Zema, M. Cerea, and A. Gazzaniga ). 7 CHRONOTHERAPY USING EGALET TECHNOLOGY ( Daniel Bar-Shalom, Clive G. Wilson, and Neena Washington ). 8 CHRONSETt: AN OROS DELIVERY SYSTEM FOR CHRONOTHERAPY ( Liang C. Dong, Crystal Pollock-Dove, and Patrick S.L. Wong ). 9 CONTROLLED RELEASE MICROCHIPS ( Karen Daniel, Hong Linh Ho Duc, Michael Cima, and Robert Langer ). 10 IMPLICATIONS AND APPLICATIONS OF CIRCADIAN SUSCEPTIBILITY RHYTHMS: CHRONOMICS AND ANESTHESIA ( Franz Halberg, Germaine Corne' lissen, and Othild Schwartzkopf f). 11 TREATMENT WITH OPEN EYES: MARKERS-GUIDED CHRONOTHERANOSTICS ( Germaine Corne lissen, and Franz Halberg ). INDEX.