Main description:

This is the definitive text introducing the new discipline of clinical and translational science. It covers all aspects of this new field, and captures the excitement of novel approaches to investigation of human health and disease, emphasizing drug discovery, interventions, and outcomes for the purposes of developing new treatment approaches, devices, and modalities to improve health. This book begins with experimental design and investigative tools. It moves on to human genetics and pharmacology with a focus on genomic science, clinical trials, epidemiology, outcomes, research, drug discovery and development, and clinical trials. It addresses legal, social and ethical issues of clinical research. It discusses practical biological, physiological, cellular, and therapeutic applications for one of the fastest growing fields in private practice and academic medicine. It includes contributions from international leaders providing insight into background and future understanding for clinical and translational science.
It presents the structure for complete instruction and guidance on the subject from fundamental principles, approaches and infrastructure to human genetics, human pharmacology, research in special populations, the societal context of human research, and the future of human research.