Main description:

Cyclodextrins in Pharmaceutics, Cosmetics, and Biomedicine covers a wide range of knowledge on cyclodextrins, from an overview of molecular and supramolecular aspects of cyclodextrin physicochemistry, to the latest outcomes in cyclodextrin use and future possibilities in the employment of these systems. This book focuses on the derivatives and physicochemical and biological properties of cyclodextrins, and considers drug delivery through topical, mucosal, and oral via cyclodextrin complexes.

Contents:

Contributors. Preface. Part I. Cyclodextrins: History, Properties, Applications, and Current Status. 1. Cyclodextrins and Their Inclusion Complexes (Dominique Duchene). 2. Cyclodextrins as Potential Excipients in Pharmaceutical Formulations: Solubilizing and Stabilizing Effetcts (Alka Ahuja, Sanjula Baboota, Javed Ali, and Gulam Mustafa). 3. Cyclodextrins as Bioavailability Enhancers (Fusun Acarturk and Nevin Celebi). 4. Cyclodextrins as Smart Excipients in Polymeric Drug Delivery Systems (Agnese Miro, Francesca Ungaro, and Fabriana Quaglia). 5. Recent Findings on Safety Profiles of Cyclodextrins, Cyclodextrin Conjugates, and Polypseudorotaxanes (Hidetoshi Arima, Keiichi Motoyama, and Tetsumi Irie). 6. Regulatory Status of Cyclodextrins in Pharmaceutical Products (A. Atilla Hincal, Hakan Eroglu, and Erem Bilensoy). 7. Cyclodextrins in the Cosmetic Field (Nilufer Tarimci). 8. Cyclodextrin-Enhanced Drug Delivery Through Mucous Membranes (Phatsawee Jansook, Marcus E. Brewster, and Thorsteinn Loftsson). 9. Applications of Cyclodextrins for Skin Formulation and Delivery (Amelie Bochot and Geraldine Piel). 10. Oral Drug Delivery with Cyclodextrins (Francisco Veiga, Ana Rita Figueiras, and Amelia Vieira). Part II. Novel and Specialized Applications of Cyclodextrins. 11. Amphiphilic Cyclodextrins: Synthesis and Characterization (Florent Perret and Helene Parrot-Lopez). 12. Gene Delivery with Cyclodextrins (Veronique Wintgens and Catherine Amiel). 13. Targeted Cyclodextrins (Stefano Salmaso and Fabio Sonvico). 14. Cyclodextrins and Biotechnological Applications (Amit Singh, Abhishek Kaler, Vachan Singh, Rachit Patil, and Uttam C. Banerjee). 15. Cyclodextrins and Cellular Interactions (Justin M. Dreyfuss and Steven B. Oppenheimer). 16. Cyclodextrins-Based Hydrogels (Carmen Alvarez-Lorenzo, Maria D. Moya-Ortega, Thorsteinn Loftsson, Angel Concheiro, and Juan J. Torres-Labandeira). 17. Cyclodextrin Nanosponges and Their Applications (Francesco Trotta). 18. Photodynamic Tumor Therapy with Cyclodextrin Nanoassemblies (Antonino Mazzaglia). 19. Sugammadex: A Cyclodextrin-Based Novel Formulation and Marketing Story (Francois Donati). 20. Cyclodextrins and Polymer Nanoparticles (Dominique Duchene and Ruxandra Gref). Index.