Main description:

Understanding how digestive organs develop, their physiology and structure is important for determining new therapies to combat diseases of the digestive organs. This volume reviews the latest research and developments in this field.

Contents:

1. Transcriptional Control of Acinar Development and Homeostasis
Raymond J. MacDonald, Galvin H. Swift, and Francisco X. Real
2. Molecular Biology of Pancreatic Ductal Adenocarcinoma Progression:Aberrant Activation of Developmental Pathways
Andrew D. Rhim and Ben Z. Stanger
3. Transcriptional Control of Hepatocyte Differentiation
Masato Nagaoka and Stephen A. Duncan
4. Molecular Mechanisms of Biliary Development
Frederic P. Lemaigre
5. Molecular determinants of liver zonation
Cyril Torre, Christine Perret, and Sabine Colnot
6. Fibrosis in the Liver: acute protection and chronic disease
Youngmin Lee and Scott L. Friedman
7. Hierarchies of transcriptional regulation during liver regeneration
Svitlana Kurinna and Michelle Craig Barton
8. Biology of the Adult Hepatic Progenitor Cell: "Ghosts in the Machine"
Houda Darwiche and Bryon E. Petersen
9. Signaling networks in human hepatocarcinogenesis - novel aspects and therapeutic options
K. Breuhahn, P. Schirmacher