Main description:

Developmental Biology and Musculoskeletal Tissue Engineering: Principles and Applications focuses on the regeneration of orthopedic tissue, drawing upon expertise from developmental biologists specializing in orthopedic tissues and tissue engineers who have used and applied developmental biology approaches. Musculoskeletal tissues have an inherently poor repair capacity, and thus biologically-based treatments that can recapitulate the native tissue properties are desirable. Cell- and tissue-based therapies are gaining ground, but basic principles still need to be addressed to ensure successful development of clinical treatments. Written as a source of information for practitioners and those with a nascent interest, it provides background information and state-of-the-art solutions and technologies.

Recent developments in orthopedic tissue engineering have sought to recapitulate developmental processes for tissue repair and regeneration, and such developmental-biology based approaches are also likely to be extremely amenable for use with more primitive stem cells.

Contents:

1. Developmental biology of musculoskeletal tissues for Tissue Engineers
2. The Mechanics of Musculoskeletal Development
3. Developmental and orthopaedic diseases
4. Synovial joint development
5. Articular and Growth plate Cartilage development
6. Bone development
7. Disc development
8. Tendon development
9. Biomimetic tissue engineering based on human development
10. Clinical translation