Main description:

This new volume of Advances in Pharmacology presents the diversity and functions of GABA Receptors. The volume looks at research performed in the past 20 years which has revealed specific physiological and pharmacological functions of individual GABAA receptor subtypes, providing novel opportunities for drug development.

Contents:

1. The Legacy of the Benzodiazepine Receptor: From Flumazenil to Enhancing Cognition in Down Syndrome and Social Interaction in Autism
Hanns Moehler
2. Behavioral Functions of GABAA Receptor Subtypes - the Zurich Experience
Florence Crestani and Uwe Rudolph
3. Allosteric Modulation of GABAA Receptors via Multiple Drug Binding Sites
Werner Sieghart
4. Regulation of GABAARs by Phosphorylation
Yasuko Nakamura, Laura M. Darnieder, Tarek Z. Deeb and Stephen J. Moss
5. Endozepines
Zoya Farzampour, Richard J. Reimer and John Huguenard
6. Inhibitory Neurosteroids and the GABAA Receptor
Sandra Seljeset, Duncan Laverty and Trevor G Smart
7. Interactions of Flavonoids with Ionotropic GABAA Receptors
Jane R Hanrahan, Mary Chebib and Graham A R Johnston
8. GABAA Receptor Partial Agonists and Antagonists: Structure, Binding Mode, and Pharmacology
Jacob Krall, Thomas Balle, Niels Krogsgaard-Larsen, Troels E. Sorensen, Povl Krogsgaard-Larsen, Uffe Kristiansen and Bente Frolund
9. Closing the Gap between the Molecular and Systemic Actions of Anesthetic Agents
Bernd Antkowiak