Main description:

Breast cancer is a complex disease caused by multiple environmental and lifestyle factors interacting with genetic susceptibility across the life span. Therefore, environmental factors are of intense interest to both researchers and community members, including women with breast cancer. There is not adequate literature that addresses this issue comprehensively from epidemiological, experimental, and translational research perspective. This book is aiming to fill this gap by gathering chapters from the most recognized experts in the field of breast biology and cancer with special interests in environmental issues.

Contents:

1 Epidemiologic Basis of the Role of Environmental
Endocrine Disruptors in Breast Cancer.....Robert A. Hiatt

2 Puberty as a Window of Susceptibility.....Frank M. Biro and Mary S. Wolff

3 In Search of the Optimal Experimental Model.....Irma H. Russo and Jose Russo

4 Early Life Exposure to Bisphenol A and Breast Neoplasia.....Maricel V. Maffini, Carlos Sonnenschein, and Ana M. Soto

5 Endocrine Disruptors Affect the Genomic Profile of the Rat
Mammary Gland at Different Developmental Stages.....Ricardo Lopez de Cicco, Julia Santucci-Pereira, Raquel Moral, Suraj Peri, Michael Slifker, Irma H. Russo, Patricia A. Russo, Richard Wang, and Jose Russo

6 Proteomic Basis for the Increased Susceptibility
of the Mammary Gland to Carcinogenesis After Perinatal
Exposure to BisphenolA.....Sarah Jenkins, Angela M. Betancourt, Jun Wang, James A. Mobley, and Coral A. Lamartiniere

7 Dioxin as an Environmental Pollutant and Its Role in Breast Cancer.....Stephen Safe, Kelcey Walker, and Shu Zhang

8 Mammary Gland as a Sensitive Tissue to Developmental Exposures of Perfluorooctanoic Acid (PFOA) in the Mouse.....Sally S. White, Suzanne E. Fenton, Chengfeng Yang, and Sandra Z. Haslamxii

9 Atrazine: An Environmental Endocrine Disruptor That Alters Mammary Gland Development and Tumor Susceptibility.....Jennifer L. Rayner and Suzanne E. Fenton

10 The Biological Impact of Radiation Exposure
on Breast Cancer Development.....David H. Nguyen, Irineu Illa Bochaca, and Mary Helen Barcellos-Hoff

11 Brain Estrogens and Metabolism.....Yong Xu and Deborah J. Clegg