Main description:

Epigenetics of the Immune System focuses on different aspects of epigenetics and immunology, providing readers with the fundamental mechanisms relating to epigenetics and the immune system. This book provides in-depth information on immune cells as a toolbox in deciphering systematically regulated mechanisms using "omics" and computational biology approaches. In addition, the book presents the translational importance of epigenetics and the immune system in our understanding of pathophysiology in diseases and its therapeutic applications.

Contents:

Preface

1. An introduction to immunology and epigenetics Jaydeep Bhat, Dieter Kabelitz

2. Plant epigenetics and the "intelligent" priming system to combat biotic stress Hemlata Kotkar, Ashok Giri

3. Understanding immune system development: An epigenetic perspective Ayush Madhok, Anjali deSouza, Sanjeev Galande

4. Epigenetic mechanisms in the regulation of lymphocyte differentiation Nina Schmolka, Bruno Silva-Santos, Anita Q. Gomes

5. Epigenetics mechanisms driving immune memory cell differentiation and function Stephen J. Turner, Jasmine Li, Brendan E. Russ

6. Microbiota in the context of epigenetics of the immune system Katarzyna Placek

7. Sequencing technologies for epigenetics: From basics to applications Rosario Michael Piro

8. Advances in single-cell epigenomics of the immune system Jonas Schulte-Schrepping, Humberto J. Ferreira, Adem Saglam, Emily Hinkley, Joachim L. Schultze

9. Machine learning and deep learning for the advancement of epigenomics Magdalena A. Machnicka, Bartek Wilczynski

10. Systems immunology meets epigenetics Wenhui Li, Ziyi Chen, Aiping Wu, F. Xiao-Feng Qin, Lianjun Zhang

11. Epigenetic deregulation of immune cells in autoimmune and autoinflammatory diseases Javier Rodriguez-Ubreva, Tianlu Li, Esteban Ballestar

12. Epigenetics of allergies: From birth to childhood Avery DeVries, Donata Vercelli

13. Epigenetic regulation of normal hematopoiesis and its dysregulation in hematopoietic malignancies Mark Hartmann, Mariam Hakobyan, Jens Langstein, Maximilian Schonung, Sina Stable, Aurore Touzart, Justyna A. Wierzbinska, Daniel B. Lipka

14. Impact of epigenetic modifiers on the immune system Sajad Ahmad Bhat, Shalini Kashipathi Sureshbabu, Chinna Susan Philip, Shubhada Chiplunkar

Index