Main description:

Leading interventional cardiologists, including Patrick Serruys, provide the gold-standard reference on the treatment of restenosis for interventional cardiologists. Dr. Serruys, who pioneered the use of drug-eluting stents, and other pioneers in the field, cover everything from non-invasive imaging, to eluting stents, to brachytherapy through to the latest molecular biology-based treatments including antisense, stem cells and gene therapy.

Contents:

Essentials of Restenosis for the Interventional Cardiologist
Table of Contents:

Part A. Introduction

Henricus J. Duckers
Caroline Cheng
Dennie Tempel
Patrick W. Serruys

Part B. Pathophysiology and Diagnosis

Chapter:

1. Epidemiology and Pathogenesis of Restenosis Randolph L. Geary
Alexander W. Clowes

2. Clinical Presentation of Restenosis Ganesh Manoharan
Giedrius Davidavicius
William Wijns

3. Pathologic Anatomy of Restenosis Renu Virmani
Frank D. Kolodgie
Aloke V. Finn
Herman K. Gold

4. The Influence of Shear Stress on Restenosis Attila Thury
Cornelis J. Slager et al.

5. Role of the Immune System in the
Pathogenesis of Vascular Proliferative Disease Jon D. Laman
Burkhard Ludewig

6. Animal Restenosis Models.
From the aEUROoeIdeal ModelaEURO? to the aEUROoeIdeal StudyaEURO? Arturo G. Touchard
Robert S. Schwartz

Part C. Genetic base of restenosis

Chapter:

7. The Genomics of Restenosis Thomas W. Johnson
Karl R. Karsch

8. Gene Expression Profiling and Restenosis Dietlind ZohlnhAfer
Franz-Josef Neumann

9. Proteomics and Restenosis Santhi K. Ganesh
Elizabeth G. Nabel

10. Contribution of circulating Progenitor Cells to
Vascular Repair and Lesion Formation. Masataka Sata
Kenneth Walsh

11. Cell Cycle Regulation in Vascular
Proliferative Diseases Andrew Wragg
Manfred Boehm

12. Arterial Remodelling Gerard Pasterkamp
Bradley H. Strauss

Dominique de Kleijn

13. The role of eNOS in vascular diseases Alexey Kuroedov
Francesco Cosentino
Felix C. Tanner
Thomas LA1/4scher

Part D. Diagnostics of Restenosis

Chapter:

14. The use of pressure gradient analysis in the
diagnosis of restenosis Volker Klaus
Nico N.H.J. Pijls

15. The Use of Radio Isotopes in the Diagnosis
ofVascular Proliferative Disease Giedrius Davidavicius
Ganesh Manoharan
William Wijns

16. Magnetic resonance imaging for restenosis Robert Jan M. van
Geuns
Timo Baks

17. Coronary Imaging with Multislice Spiral
Computed Tomography Koen Nieman

Part E. Therapy of Restenosis

Chapter:

18. Pharmacotherapy of Restenosis Pim J. de Feyter
Georgios Sianos

19. Brachytherapy Ron Waksman

20. Pre-clinical Data of Eluting Stents Antonio Colombo
Alaide Chieffo

21. Clinical Data of Eluting Stents Marco A. Costa
Alexandre Abizaid
Amanda G.M.R. Sousa
Eduardo Sousa

22. Biodegradable stents Takafumi Tsuji
Hideo Tamai

Keiji Igaki

Part F. Biotechnology in the Treatment of Restenosis

Chapter:

23. Vascular Gene Therapy Gurpreet S. Sandhu
Robert D. Simari

24. Antisense and ODN transcription factors
in the treatment of Vascular Proliferative Disease Nicholas Kipshidze
Mykola Tsapenko
George Dangas
Pat Iversen

25. Cell Cycle Approaches to the
Treatment of In-stent Restenosis Elizabeth G. Nabel

26. Local Gene and Cell Delivery Devices Ravish Sachar
Eric J. Topol