Main description:

This volume provides a full explanation and technical details to perform surgical techniques properly on small and large animal models. The first six chapters of Experimental Neurosurgery in Animal Models focus primarily on the brain, while the next six chapters concern the spinal cord in rodents. The last four chapters provide a description of operative procedures in large animals. Written for the popular Neuromethods series, chapters include the kind of detail and key implementation advice that ensures successful results in the laboratory.

Authoritative and practical, Experimental Neurosurgery in Animal Models aims to ensure successful results in the further study of this vital field.

Contents:

1. Animal Models of Traumatic Brain Injury

Fredrik Clausen

2. Experimental Radiosurgery in Animal Models Ajay Niranjan, Wendy Fellows-Mayle, Douglas Kondziolka,and L. Dade Lunsford

3. Stereotactic Surgery in Rats

Jaroslaw Maciaczyk, Ulf D. Kahlert, Mate Doebroessy, and Guido Nikkhah

4. Rat Middle Cerebral Artery (MCA) Occlusion Models Which Involve a Frontotemporal Craniectomy

Hideaki Imai, Nobuhito Saito, and I Mhairi Macrae

5. Inferior Colliculus Approach in a Rat

Dennis T.T. Plachta

6. Why Robots Entered Neurosurgery

Jason W. Motkoski and Garnette R. Sutherland

7. Impact Model of Spinal Cord Injury

Dorothee Cantinieaux, Rachelle Franzen, and Jean Schoenen

8. Acute Clip Contusion Compression Model of SCI

Jared T. Wilcox and Michael G. Fehlings

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9. Microsurgical Approach to Spinal Canal in Rats

Mortimer Gierthmuehlen and Jan Kaminsky

10. Stereotaxic Injection into the Rat Spinal Cord

Charla C. Engels and Piotr Walczak

11. Surgical Access to Cisterna Magna Using Concorde-Like Position for Cell Transplantation in Mice and CNS Dissection within Intact Dura for Evaluation of Cell Distribution

Miroslaw Janowski

12. Animal Models for Experimental Neurosurgery of Peripheral and Cranial Nerves

Joachim Oertel, Christoph A. Tschan, and Doerther Keiner

13. Surgery of the Brain and Spinal Cord in a Porcine Model

Jan Regelsberger

14. Real-Time Convection Delivery of Therapeutics to the Primate Brain

Dali Yin, Massimo S. Fiandaca, John Forsayeth, and Krystof S. Bankiewicz

15. Focal Cerebral Ischemia by Permanent Middle Cerebral Artery Occlusion in Sheep - Surgical Technique, Clinical Imaging, and Histopathological Results

Bjoern Nitzsche, Henryk Barthel, Donald Lobsien, Johannes Boltze, Vilia Zeisig, and Antje Y. Dreyer

16. A Non-Human Primate Model of Delayed Cerebral Vasospasm after Aneurismal Subarachnoid Hemorrhage Ryszard M. Pluta, John Bacher, Boris Skopets, and Victoria Hoffmann