Main description:

The `Formation of the Heart and its Regulation` reviews in considerable
detail the major events in heart development and their control via
genes, cell-cell interactions, growth factors and other contributing
elements. In addition, there is an extensive and useful overview of the
field of heart development taken as a whole.
The book will appeal to all students and researchers working on
cardiovascular development and to pediatric cardiologists.

Contents:

Foreword. Edward B. Clark. Preface. 1. Overview of Heart Development. Roger R. Markwald and Andy Wessels. 2. Myofibrillogenesis in the Heart. Carol C. Gregorio and Parker B. Antin. 3. Cardiac Looping and the Left-Right Axis: Integrating Morphological Molecular and Genetic Analyses of Vertebrate Left-Right Asymmetry. Ann F. Ramsdell and H. Joseph Yost. 4. Differentially Expressed Genes and Cardiac Morphogenesis. Jim J-C. Lin, Da-Zhi Wang, Rebecca S. Reiter, Qin Wang, Jenny L-C. Lin, and Haley S. Williams. 5. Molecular Mechanisms of Cardiac Diversification. Jeffrey D. Croissant, Stacey Carpenter, and David Bader . 6. Neural Crest and Heart Development. Margaret L. Kirby. 7. Cardiac Conduction System Development. Takashi Mikawa, Robert G. Gourdie, Jeanette Hyer, and Kimiko Takebayashi-Suzuki. 8. The Epicardium and the Formation of the Coronary Vasculature. Robert E. Poelmann, Mark Paul F.M. Vrancken Peeters, Adriana C. Gittenberger-de Groot. 9. The Role of the Extracellular Matrix and Its Receptors in Modulation Cardiac Development. Edie C. Goldsmith, Wayne Carver and Thomas K. Borg. 10. Growth Factor Regulation of Embryonic, Fetal and Neonatal Cardiac Development. Robert L. Price, Jay D. Potts, Thomas E. Thielen, Thomas K. Borg, Louis Terracio. 11. TGFss Signal Transduction in the Atrioventricular Canal During Heart Development. Angelique S. Boyer and Raymond B. Runyan. 12. Homocysteine and the NMDA Receptor: Are They Keys to Conotruncal Abnormalities? Thomas H. Rosenquist and Daniel T. Monaghan. 13. Function and Biomechanics of Developing Cardiovascular Systems. Bradley B. Keller. Index.