Main description:

Diabetes mellitus is a disease with tremendous health and economic burden. A better understanding of how normal glucose homeostasis is maintained and the pathogenesis is important to identify new ways for diabetes treatment. This book addresses multiple aspects of this area of research.

Contents:

G Protein-Coupled Receptors as Regulators of Glucose Homeostasis and Therapeutic Targets for Diabetes Mellitus
Ya-Xiong Tao and Xu-Fang Liang
Regulation of Glucose Homeostasis by GLP-1
Prashant Nadkarni, Oleg G. Chepurny and George G. Holz
Physiology and Therapeutics of the Free Fatty Acid Receptor GPR40
Hui Huang, Meng-Hong Dai and Ya-Xiong Tao
Targeting GPR119 for the Potential Treatment of Type 2 Diabetes Mellitus
Xiu-Lei Mo, Zhao Yang and Ya-Xiong Tao
Enhanced Skeletal Muscle for Effective Glucose Homeostasis
Jinzeng Yang
Factors Affecting Insulin-regulated Hepatic Gene Expression
Hong-Ping Guan and Guoxun Chen
Roles of Peroxisome Proliferator-Activated Receptors (PPARs) in the Metabolic Syndrome
Mahmoud Mansour
Free Fatty Acids and Skeletal Muscle Insulin Resistance
Lyudmila I. Rachek
Adiponectin Signaling and Metabolic Syndrome
Yuchang Fu
Regulation of Pancreatic Islet Beta-Cell Mass by Growth Factor and Hormone Signaling
Yao Joyce Huang and Yongchang Chang
The Impact of Dietary Methionine Restriction on Biomarkers of Metabolic Health
Manda L. Orgeron, Kirsten P. Stone, Desiree Wanders, Cory C. Cortez, Nancy T. Van and Thomas W. Gettys
Carbohydrate Metabolism and Pathogenesis of Diabetes Mellitus in Dogs and Cats
Margarethe Hoenig
Impaired Insulin Signaling and Mechanisms of Memory Loss
Jenna Bloemer, Subhrajit Bhattacharya, Rajesh Amin and Vishnu Suppiramaniam
The Role of PPARd Signaling in the Cardiovascular System
Yishu Ding, Kevin D. Yang and Qinglin Yang