Main description:

Custom-designed for clinicians on the frontline of treatment and prevention of the human papillomavirus (HPV), this stand-alone handbook provides the scientific background needed to understand and administer the new HPV vaccines. Written by some of the discoverers of these vaccines, this accessible text explores the biology and epidemiology of HPV, its diagnosis, screening, prevention, and treatment, and the types of diseases linked to the virus.

The Guide to Genital HPV Diseases and Prevention:

aids clinicians in addressing patient questions and concerns
discusses the basic virology and pathogenesis of HPV
explores the relationship between HPV and cancer, especially cancer of the cervix
covers the various treatment methods, including both chemical and physical methods
details prevention strategies, such as condoms and microbicides, and vaccines (Gardasil, Cervarix, Silgard, and those in development)
is an essential reference for an array of clinicians, including family practice physicians, internal medicine specialists, pediatricians, dermatologists, gynecologists, and oncologists

Contents:

Preface. Overview. 1: Biology. Basic Virology. Structure. Classification and Disease Association. Genome Organization. Viral Proteins. Growth in Cell Cultures and Animal Models. Antigenicity. Pathogenesis. Molecular and Cellular Pathogenesis. Active Infection. Oncogenesis. Latency. Immunology. Humoral Response. Cellular Innate and Adaptative Response. References. 2: Epidemiology. Incidence and Prevalence. Risk Factors. HPV and Cancer, the Casual Link. Transmission and Reinfection. Natural History. References. 3: HPV Diseases. External Anogenital Warts. Other Diseases of the Anogenital Tract. Diseases of the Head and Neck Area. References. 4. Treatment. The Armamentarium. Chemical Methods. Physical Methods. Approach to Treatment. External Anogenital Warts. Other Diseases of the Anogenital Tract. Diseases of the Head and Neck Area. References. 5: Diagnosis. Cytology and Colposcopy. Histology. Nucleic Acid Detection Methods. Serology. References. 6: Screening. Screening Strategies. Appropriate Use of HPV DNA Testing. New Screnning Markers. References. 7: Prevention. Condoms and Microbicides. Vaccination. Vaccine Preclinical and Early Clinical Development. Gardasil/Silgard. Clinical Trials. Phase I Studies. Phase II Studies. Phase III and IV Studies. The Vaccine. Vaccine Recommendations. Availability. Duration of Immunity. Contraindications. Adverse Events. Cervarix. Clinical Trials. Phase I Studies. Phase II Studies. Phase III and IV Studies. The Vaccine. Vaccine Recommendations. Availability. Duration of Immunity. Contraindications. Adverse Events. Other Vaccines in Development. Benefits, Obstacles, and Strategies to Implement HPV Vaccination. Unanswered Questions. References.