Main description:

This book presents an authoritative review of analytical methods used for diagnostics, medical therapy and for forensic purposes. Divided into 4 parts, the book discusses new challenges in bioanalytics, covers bioanalysis as a source of clinical, pharmaceutical and forensic information, explores natural resources as a source of biologically active compounds, and offers new analytical strategies and equipment solutions. Written by interdisciplinary expert academics, this work will appeal to a wide readership of students, researchers and professionals interested in the fields of medicine, chemistry, pharmaceutical, life and health sciences, engineering and environmental protection. Clinicians and employees of forensic laboratories will also find this work instructive and informative.

Contents:

Bioanalytics in in Vitro and in Vivo Transformation of Biologically Active Compounds for the Needs of Biomedical Diagnostics.- Mass Spectrometry-based Proteomic Analysis in Neurodegenerative Disorders' Research.- Medical Bioanalytics - Separation Techniques in Medical Diagnostics of Neurological Diseases and Disorders on Selected Examples.- Analysis of Endogenous Metabolites in Human Matrices.- Analytics of Antisense Oligonucleotides.- Analytical Approaches to Assessment of Phospholipid Metabolism in Physiology and Pathology.- Analytical Strategies and Applications in Lipidomics.- Lipidomics in Morbid Obesity.- Analysis of Basic Psychotropic Drugs in Biological Fluids and Tissues by RP-HPLC Method.- Detection of Psychoactive Substances Used in Doping: Screening and Confirmation Procedures.- Application of Separation Techniques in Analytic of Biologically Relevant Sulfur Compounds.- Application of Planar Chromatography in Pharmaceutical, Clinical and Toxicological Analysis.- Volatile Organic Compounds Emitted by Biological Matrices.- Human Milk and Xenobiotics.- Recent Advances in the Forensic Dating of Blood Traces: a Minireview.- Analysis of Biological Samples Using Vibrational Spectroscopy Methods.