Main description:

Methadone and buprenorphine are the only two opioids that are indicated for the management of both pain and opioid-related drug addiction. Both present unique challenges to the general practitioner and pain specialist, requiring a separate analysis from the rest of the drugs in the same family.

Handbook of Methadone Prescribing and Buprenorphine Therapy is an invaluable guide to the safe use of these opioids. Authored by clinical and academic leaders from a variety of settings and backgrounds, this book includes chapters on pharmacology, adverse effects, safe rotation from other opioids, cardiac toxicity, prescribing, pharmacokinetics, equianalgesic dose and replacement therapy.

This comprehensive text provides clinicians, researchers, policy-makers and academicians a resource for all the relevant points in methadone prescribing and buprenorphine therapy.

Contents:

Foreward

Russell K. Portenoy MD

Preface

Ricardo A. Cruciani, MD, PhD & Helena Knotkova, PhD

Prescribing Methadone Safely

Eliezer Soto MD, Joy Hao MD, PhD, Helena Knotkova PhD, Ricardo A. Cruciani MD, PhD

Use of Methadone in Opioid Maintenance Treatment

Dr. Randy M. Seewald, MBBS

Treating Pain in Patients Receiving Methadone Maintenance for Opioid Dependence

Daniel P. Alford, MD, MPH, Declan T. Barry, PhD, & David A. Fiellin, MD

Methadone Side Effects: Constipation, Respiratory Depression, Sedation, Sleep-Disordered Breathing, and the Endocrine System

Lynn R. Webster, MD

Cardiovascular Effects of Methadone

Miguel A. Leal, MD & Craig T. January, MD, PhD

Methadone Pharmacodynamics and Pharmacokinetics

Gavin Bart, MD & Sharon L. Walsh PhD

Methadone and opioid rotation

Helena Knotkova PhD, Ricardo A. Cruciani,MD, PhD, Perry G. Fine MD

Intravenous use of Methadone: efficacy and safety

Sebastiano Mercadante, MD

Methadone Hyperalgesia

Peggy Compton, RN, PhD, FAAN

Buprenorphine Analgesia in Chronic Pain

Guy Hans, MD, PhD

Buprenorphine in Maintenance Therapy

Karran A. Phillips, MD, MSc & Kenzie L. Preston, PhD

Buprenorphine Pharmacodynamics and Pharmacokinetics

Sharon L. Walsh, PhD & Lisa S. Middleton, PhD

13. Buprenorphine metabolism and drug-drug interactions

Robert Taylor Jr., PhD, Robert B. Raffa, PhD, & Joseph V. Pergolizzi Jr., MD

Buprenorphine: side effects and tolerability

Tabitha Washington, MD, MS & Gilbert J. Fanciullo, MD, MS

Buprenorphine and Opioid Rotation

Douglas L. Gourlay, MD, MSc, FRCP, FASAM & Howard A. Heit MD, FACP, FASAM

Methadone and buprenorphine use during the perinatal period

Alice Ordean MD, CCFP, MHSc

Methadone and Buprenorphine Prescribing in the Palliative Care Population

Shalini Dalal MD & Eduardo Bruera MD

Methadone Prescribing In The Sickle Cell Patient

Wally R. Smith, MD & Abdulkhaliq J. Alsalman, MS

Methadone and Buprenorphine Analgesia in Older Patients

David Lussier, MD, FRCP(c)