Main description:

Over the last decade the science and medicine of high altitude and hypoxia adaptation has seen great advances. High Altitude: Human Adaptation to Hypoxia addresses the challenges in dealing with the changes in human physiology and the particular medical conditions that arise from exposure to high altitude. In-depth and comprehensive chapters cover both the basic science and the clinical consequences of exposure to high altitude. Genetic, cellular, organ and whole body system responses to high altitudes are covered and chapters discuss these effects on a wide range of diseases. Expert authors provide insight into the care of patients with pre-existing medical conditions that fail in some cases to adapt as well as offer insights into how high altitude research can help critically ill patients. High Altitude: Human Adaptation to Hypoxia is an important new volume that offers a window into greater understanding and more successful treatment of hypoxic human diseases.

Contents:

High Altitude: Human Adaptation to Hypoxia:

1. Cellular and Molecular Mechanisms of O2 Sensing

Paul T. Schumacker

2. Cell and Molecular Defenses Against Hypoxia

Stilla Frede and Joachim Fandrey

3. Control of Breathing

Luc J. Teppema and Remco R. Berendson

4. Lung Function and Gas Exchange

Andrew M. Luks and Susan R. Hopkins

5. Pulmonary Circulation

Marco Maggiorini, Peter Bartsch, and Erik R Swenson

6. Cardiovascular System

Aaron L. Baggish, Eugene E. Wolfel, and Benjamin D. Levine

7. Cerebral Circulation and Brain

Philip N. Ainslie, Mark H. Wilson, and Christopher HE Imray

8. Autonomic Nervous System

Roger Hainsworth, Mark J. Drinkhill, and Victoria E. Claydon

9. Skeletal Muscle

Hans Hoppeler, Matthias Mueller, and Michael Vogt

10. Blood and Hemostasis

Peter Bartsch and Jim Milledge

11. Renal Function and Fluid Balance

Erik R. Swenson and Niels V. Olsen

12. Endocrine Function

Jean-Paul Richalet

13. Gastrointestinal Function

Noor Hamad and Simon Travis

14. Immune System

Robert S. Mazzeo and Erik R. Swenson

15. Nutrition and Metabolism

George A. Brooks

16. Exercise

Carsten Lundby

17. Sleep

Yvonne Nussbaumer-Ochsner and Konrad E. Bloch

18. Reproduction and Growth

Susan Niermeyer

19. Human Evolution at High Altitude

Cynthia M. Beall

20. Acute Mountain Sickness and High-Altitude Cerebral Edema

Peter Bartsch and Damian Miles Bailey

21. High-Altitude Pulmonary Edema

Robert B. Schoene and Erik R. Swenson

22. Subacute and Chronic Mountain Sickness

Fabiola Leon-Velarde S, Maria Rivera-Ch, and Francisco C. Villafuerte

23. High Altitude and Common Medical Conditions

Andrew M. Luks and Peter H. Hackett