Main description:

This volume covers the latest advances in the mechanisms of pathogenesis of the HIV-1 virus on target cells. Its companion volume, Advances in Pharmacology 56, shows how new developments in understanding the virus translate to the clinical setting.

Contents:

HIV-1 RNA Packaging Structure and Function of the HIV Envelope Glycoprotein as Entry Mediator, Vaccine Immunogen, and Target for Inhibitors HIV-1 Reverse Transcription: Close Encounters Between the Viral Genome and a Cellular tRNA Transcription of HIV: Tat and Cellular Chromatin Posttranscriptional Control of HIV-1 and Other Retroviruses and Its Practical Applications HIV Accessory Genes Vif and Vpu Interactions of HIV-1 Viral Protein R with Host Cell Proteins HIV-1 Protease: Structure, Dynamics, and Inhibition Properties, Functions, and Drug Targeting of the Multifunctional Nucleocapsid Protein of the Human Immunodeficiency Virus Human Immunodeficiency Virus Type 1 Assembly, Release, and Maturation Role of Nef in HIV-1 Replication and Pathogenesis Treatment Implications of the Latent Reservoir for HIV-1 RNA Interference and HIV-1