Main description:

Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics. This volume covers hyaluronan signaling and turnover.

Contents:

1.Emerging Roles for Hyaluronidase in Cancer Metastasis and Therapy
2.Targeting Hyaluronic Acid Family for Cancer Chemoprevention & Therapy
3.Aberrant Post-Transcriptional Processing of Hyaluronan Synthase 1 in Malignant Transformation and Tumor Progression
4.Hyaluronan Synthases Post-Translational Regulation in Cancer
5.Hyaluronon-Coated Extracellular Vesicles - A Novel Link Between Hyaluronan and Cancer
6.Hyaluronan in the Healthy and Malignant Hematopoietic Microenvironment
7.Hyaluronan Regulation of Endothelial Barrier Function in Cancer
8.HAS2 and CD44 in Breast Tumorigenesis
9.CD44 is a Multidomain Signaling Platform that Integrates Extracellular Matrix Cues with Growth Factor and Cytokine Signals
10.Hyaluronan-CD44 Interaction Promotes Oncogenic Signaling, MicroRNA Functions, Chemoresistance and Radiation Resistance in Cancer Stem Cells Leading to Tumor Progression
11.Advances and Advantages of Nanomedicine in the Pharmacological Targeting of Hyaluronan-CD44 Interactions and Signaling in Cancer
12.Hyaluronan / RHAMM Interactions in Mesenchymal Tumor Pathogenesis: Role of Growth Factors
13.CD147: Regulator of Hyaluronan Signaling in Invasiveness and Chemoresistance