Main description:

Immune Rebalancing: The Future of Immunosuppression summarizes the most promising perspectives of immunopharmacology, in particular in the area of immunosuppression by considering molecular pathways, personalized medicine, microbiome and nanomedicine.

Modulation of immune responses for therapeutic purposes is a particularly relevant area, given the central role of anomalous immunity in diseases. These diseases vary from the most typically immune-related syndromes (autoimmune diseases, allergy and asthma, immunodeficiencies) to those in which altered immunity and inflammation define the pathological outcomes (chronic infections, tumours, chronic inflammatory and degenerative diseases, metabolic disorders, etc.

Contents:

1. Pharmacological strategies using biologics as immunomodulatory agents (Introduction)
2: Mechanisms of immune-related pathologies and their current treatment
2.1 Rheumatoid arthritis
2.2 IBD and Crohn's disease
2.3 MS and neurodegenerative diseases
2.4 Allergic diseases
2.5 Cancer
3: Biologics as immunosuppressive agents
3.1 Modulating macrophage activity
3.2 Modulatig inflammatory cytokines: IL-1
4. Systems medicine and personalised medicine
5. Modulation of the microbiome for immune re-balancing
6. Natural products
7. Nanomedicine