Main description:

Inflammation and Oral Cancer: From Bench to Bedside discusses all aspects surrounding the relationship between inflammation and oral cancer, from basic science to the translational research that helps in the optimization of clinical management strategies. The book discusses topics such as chronic inflammation and cancer in oral cavity, the role of HPV in oral inflammation and cancer, rodent models of oral cancer, and epigenetics in oral inflammation and cancer. This is a valuable resource for cancer researchers, oncologists and members of biomedical field who are interested in learning more about the diverse aspects of inflammation and oral cancer.

Inflammation in oral mucosa can remodel the topography of the overlying epithelium. If such inflammation is chronic, it can have fundamental clinical consequences, the principal of which can be premalignant lesions throughout the alimentary tract. Furthermore, mucosal inflammation, even if subtle, is the single most common pathway for oral cancer - therefore it is very important to understand these interactions in detail.

Contents:

1. Epidemiology of oral cancer and its relationship with inflammation
Katsuaki Bunai
2. Diagnosis of oral squamous cell carcinomas and precancerous lesions
Keisuke Nakano and Hitoshi Nagatsuka
3. Oral cytology in Japan: Its useful approach and criteria for early detection of carcinoma and precursor lesions
Motohiko Nagayama, Akinori Ihara, and Yoichi Tanaka
4. Imaging findings of oral cancers
Hiroki Kato and Masayuki Matsuo
5. What is epigenetics?
Keizo Kato
6. Role of autophagy in dysregulation of oral mucosal homeostasis
Madoka Yasunaga, Masahiro Yamaguchi, Kei Seno, Mizuki Yoshida, and Jun Ohno
7. Oral mucosal graft-versus-host disease and its possibility of antitumor effects
Kei Seno, Madoka Yasunaga, Nana Mori-Yamamoto, and Jun Ohno
8. Standardization of sentinel lymph node biopsy in oral cancer
Kazuhisa Ishida
9. Overview of radiotherapy for oral cavity cancer
Chiyoko Makita, Masaya Ito, Hirota Takano, Tomoyasu Kumano, and Masayuki Matsuo
10. Management of cancer treatment-induced oral mucositis
Akio Suzuki
11. Perspectives in research on oral squamous cell carcinoma
Hiroyuki Tomita