Main description:

Inflammatory breast cancer is the most deadly subtype of breast cancer because it can spread to other organs despite of multidisciplinary approach. However, the molecular characteristic of this aggressive disease is yet to be established. This book is the one of the few textbooks that summarizes the latest information dated to inflammatory breast cancer. The uniqueness of this book is that it has summarized the latest molecular and mechanistic findings, which may lead to novel diagnostic tool or therapeutic approach to fight this deadly disease.

Contents:

Introduction: Why IBC Now.-1. Epidemiology.-2 Diagnosis, Criteria and Controversy.-3 IBC Registration Study.-4 Pathology: Histomorphometrical Features Of IBC: Angiogenesis, Lymphangiogenesis, and Tumor Emboli.-5 Staging and Imaging.-6 Surgery.-7 Radiation Therapy.-8 Systemic Therapies.-9 Metastatic Treatment by Chemotherapy.-10 Role of Multidisciplinary Team Formation.-11 Role of High-Dose Chemotherapy.-12 Cell Line and Animal Models.-13 Signal Pathway in IBC.-14 Molecules That Drives the Metastasis and Invasion.-15 Inflammation.-16 Immunological Changes.-17 Angiogenesis and Lymphoangiogenesis.-18 Microarray Analysis Identifies a Peculiar IBC Expression Signature.-19 Stem Cell Gene Expression Signature in IBC.-20 The Effect of Systemic Chemotherapy on Minimal Residual Disease in The Blood And Bone Marrow Of Patients With IBC.-21 Patient's Perspective.Index